DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18810 and ZDHHC9

DIOPT Version :9

Sequence 1:	NP_652670.2	Gene:	CG18810 / 59171	FlyBaseID:	FBgn0042133	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001008223.1	Gene:	ZDHHC9 / 51114	HGNCID:	18475	Length:	364	Species:	Homo sapiens

Alignment Length:	191	Identity:	48/191 - (25%)
Similarity:	79/191 - (41%)	Gaps:	67/191 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FLFLFILCGLPAIY------YVLMEIILPELSDYWSPGY-VFQLLLGLFLFSNVMSNYVMCILVD 75
            :|.||::.|...::      |:.:::         ||.. ||..:  |||||  |:..:.....|
Human    39 YLTLFLILGTCTLFFAFECRYLAVQL---------SPAIPVFAAM--LFLFS--MATLLRTSFSD 90

  Fly    76 PSIDPKLM---------------------------------KNQLVRGQHSEDWHECDKCGILAP 107
            |.:.|:.:                                 .||:|:.::      |..|.|..|
Human    91 PGVIPRALPDEAAFIEMEIEATNGAVPQGQRPPPRIKNFQINNQIVKLKY------CYTCKIFRP 149

  Fly   108 PRSRHCRKCGVCVLMRDHHCFFTGCCIGHENYRYFFYFLIYFFLSCMISLTSSSIFIYVLH 168
            ||:.||..|..||...||||.:.|.|:|..|||||:.|:        :||:..:|:::..:
Human   150 PRASHCSICDNCVERFDHHCPWVGNCVGKRNYRYFYLFI--------LSLSLLTIYVFAFN 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18810	NP_652670.2	zf-DHHC	92..>138	CDD:303066	18/45 (40%)
ZDHHC9	NP_001008223.1	DHHC	138..261	CDD:396215	27/79 (34%)
ZDHHC9	NP_001008223.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..364
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810