DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18810 and Zdhhc12

DIOPT Version :9

Sequence 1:	NP_652670.2	Gene:	CG18810 / 59171	FlyBaseID:	FBgn0042133	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001013257.1	Gene:	Zdhhc12 / 366014	RGDID:	1306593	Length:	267	Species:	Rattus norvegicus

Alignment Length:	237	Identity:	60/237 - (25%)
Similarity:	91/237 - (38%)	Gaps:	30/237 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ELSDYWSPGYVFQLLLGLFLFSNVMSNYVMCILVDPSI---------DPKLMKNQLVRGQHSEDW 96
            ||..:...|.:|..|..|.|....:..|:...|:||..         :||  :.|......:...
  Rat    34 ELRQWEEQGELFLPLTFLLLVLGSLLLYLAVSLMDPGYVTAQPQPQEEPK--EEQTAMVPQAIPL 96

  Fly    97 HECDKCGILAPPRSRHCRKCGVCVLMRDHHCFFTGCCIGHENYRYFFYFLIYFFLSCMISLTSSS 161
            ..|..|.:|.|.|:||||:|..||...||||.:...|:|..|:.   .|:.|..|..::.|..
  Rat    97 RRCRYCLVLQPLRARHCRECRRCVRRYDHHCPWMENCVGERNHP---LFVAYLALQLVVLLWG-- 156

  Fly   162 IFIYVLHGGRYQLFMLTHPAPNSAYFNSLIIRIIYFKLPDIYELVFTLVFVLLWIGVCVATYVAY 226
              :|:...| .|.|.     |...:..|..:....|.|...:.||.:|: :...:.:.......:
  Rat   157 --LYLAWSG-LQFFQ-----PWGLWLRSTGLLFTTFLLLSFFALVVSLL-LASHLYLVARNTTTW 212

  Fly   227 DQWSRGYFCYDFELQNIPFDRKLRRNFKTFLGRRMKWTWISG 268
            :..|.....|..:..:.||||...||...|.     ..|.||
  Rat   213 EFISSHRIAYLRQRTSNPFDRGPTRNLAHFF-----CGWPSG 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18810	NP_652670.2	zf-DHHC	92..>138	CDD:303066	18/45 (40%)
Zdhhc12	NP_001013257.1	DHHC	<123..217	CDD:396215	22/107 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900