DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18810 and Zdhhc6

DIOPT Version :9

Sequence 1:	NP_652670.2	Gene:	CG18810 / 59171	FlyBaseID:	FBgn0042133	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_001032741.1	Gene:	Zdhhc6 / 361771	RGDID:	1304657	Length:	413	Species:	Rattus norvegicus

Alignment Length:	270	Identity:	69/270 - (25%)
Similarity:	105/270 - (38%)	Gaps:	61/270 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 YW----SPGYV-FQLLLGLFLFSNVMSNYVMCILVDPSIDPKLMKNQLVRGQHSEDWHECDKCGI 104
            ||    :.|.| |.:|:...:.  ::.||...:...|...|:..|.:  ..|.|.....|..|..
  Rat    46 YWPLHTTGGSVNFIMLINWTVM--ILYNYFNAMFAGPGFVPRGWKPE--NPQDSMYLQYCKVCQA 106

  Fly   105 LAPPRSRHCRKCGVCVLMRDHHCFFTGCCIGHENYRYFFYFLIYFFLSCMISLTSSSIFIYVLHG 169
            ...|||.|||||..||:..||||.:...|.||:|:..|..||:...|.|     :.:.||:|:
  Rat   107 YKAPRSHHCRKCNRCVMKMDHHCPWINNCCGHQNHASFTLFLLLAPLGC-----THAAFIFVM-- 164

  Fly   170 GRY-QLFMLTHPAPNSAYFNSLIIR-----IIYFKLPDIYELVFTLVFVL-----------LWIG 217
            ..| ||:.......|:...:....|     |:.|.|......:|.|...|           :.|.
  Rat   165 TMYTQLYNRLSFGWNTVKIDMSAARRDPPPIVPFGLAAFAATLFALGLALGTTIAVGMLFFIQIK 229

  Fly   218 VCVATYVAYDQWSR-------GYFCYDFELQNIPFDRKLRRNFKTFLGRRMK-----WTWISGFV 270
            :.:....:.:.|..       .|:..| |:...|:|          :|.:.|     :|| || |
  Rat   230 IILRNKTSIESWIEEKAKDRIQYYQLD-EVFVFPYD----------MGSKWKNLKQVFTW-SG-V 281

  Fly   271 PSQLDHDGFD 280
            |   :.||.:
  Rat   282 P---EGDGLE 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18810	NP_652670.2	zf-DHHC	92..>138	CDD:303066	20/45 (44%)
Zdhhc6	NP_001032741.1	DHHC	95..241	CDD:396215	41/152 (27%)
Zdhhc6	NP_001032741.1	SH3_2	317..394	CDD:400139
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810