DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18810 and Zdhhc17

DIOPT Version :9

Sequence 1:NP_652670.2 Gene:CG18810 / 59171 FlyBaseID:FBgn0042133 Length:300 Species:Drosophila melanogaster
Sequence 2:NP_766142.2 Gene:Zdhhc17 / 320150 MGIID:2445110 Length:632 Species:Mus musculus


Alignment Length:230 Identity:52/230 - (22%)
Similarity:81/230 - (35%) Gaps:78/230 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    99 CDKCGILAPPRSRHCRKCGVCVLMRDHHCFFTGCCIGHENYRYF---FYFLI------------Y 148
            |..|.|..|.||:||..|..|:...||||.:.|.|:|..|:|||   .:||:            |
Mouse   439 CSTCLIRKPVRSKHCGVCNRCIAKFDHHCPWVGNCVGAGNHRYFMGYLFFLLFMICWMIYGCVSY 503

  Fly   149 FFLSCMISLTSSSIFIYVLHGGRYQLFMLTHPAPNSAYFNSLIIRIIYFKLPDIYELVFTLVFVL 213
            :.|.|..:.|....:.|:           |..|..|               |.::.:....||..
Mouse   504 WGLHCETTYTKDGFWTYI-----------TQIATCS---------------PWMFWMFLNSVFHF 542

  Fly   214 LWIGVCVATYVAYDQWSRGYFCYDFELQNIPFDRKLRRNFKTFLGRRMKWTWISGFVPSQLDH-- 276
            ||:.|.:             .|..:::..:......|.|.:.:  :..|.|..|  :.|..:|  
Mouse   543 LWVAVLL-------------MCQLYQITCLGITTNERMNARRY--KHFKVTTTS--IESPFNHGC 590

  Fly   277 -----DGFDLDPDNER--------VADWCSETTIK 298
                 |.|:.     |        :.||..:.||:
Mouse   591 VRNIIDFFEF-----RCCGLFRPVIVDWTRQYTIE 620

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18810NP_652670.2 zf-DHHC 92..>138 CDD:303066 17/38 (45%)
Zdhhc17NP_766142.2 Necessary and sufficient for interaction with DNAJC5 and SNAP25. /evidence=ECO:0000269|PubMed:25253725 11..305
ANK repeat 89..120 CDD:293786
PHA03095 100..>352 CDD:222980
ANK repeat 122..154 CDD:293786
ANK repeat 156..187 CDD:293786
Ank_2 161..255 CDD:372319
ANK repeat 189..221 CDD:293786
ANK repeat 224..255 CDD:293786
DHHC 438..568 CDD:366691 39/167 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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