Protein Alignment CG18810 and ZDHHC1

DIOPT Version :10

• Sequence 1: NP_652670.2
• Gene: CG18810 / 59171
• FlyBaseID: FBgn0042133
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_037436.1
• Gene: ZDHHC1 / 29800
• HGNCID: 17916
• Length: 485
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 66/279 - (23%)
• Similarity: 112/279 - (40%)
• Gaps: 67/279 - (24%)

  Fly     4 RSLKN--IWPKEKLEQFLFLFILCGLPAIYYVLM--EIILPELSDYWSP-GYVFQLLLGLFLFSN 63
            ||.:|  .||...|:      |:..|..:::.::  .|::|.|..:|.| ||.   .:|. :|:.
Human    38 RSRRNGWSWPPHPLQ------IVAWLLYLFFAVIGFGILVPLLPHHWVPAGYA---CMGA-IFAG 92

  Fly    64 VMSNYVMCILVDP---SIDPKLMKNQLV---RGQHS---EDWHECDKCGILAPPRSRHCRKCGVC 119
            .:..::..:.:||   ::..|.....|.   |.||:   ||.| |:.|.:....||:||..|..|
Human    93 HLVVHLTAVSIDPADANVRDKSYAGPLPIFNRSQHAHVIEDLH-CNLCNVDVSARSKHCSACNKC 156

  Fly   120 VLMRDHHCFFTGCCIGHENYRYFF------------------YFLIYFFLSCMISLTSSSIFIYV 166
            |...||||.:...|:|..|||.|.                  |..:.||::.|...|:....:..
Human   157 VCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLVLVATYVFVEFFVNPMRLRTNRHFEVLK 221

  Fly   167 LHGGRYQLFMLTHPAPNSAYFNSLIIRIIYFKLPDIYELVFTLVFV------LLWIGVCVATYVA 225
            .|...:.:|:...|....|              |.|..|...|:.:      ||...:|...|:.
Human   222 NHTDVWFVFLPAAPVETQA--------------PAILALAALLILLGLLSTALLGHLLCFHIYLM 272

  Fly   226 YDQWSRGYFCYDFELQNIP 244
            :.:.:    .|::.:|:.|
Human   273 WHKLT----TYEYIVQHRP 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18810	NP_652670.2	DHHC	92..>138	CDD:418707	19/48 (40%)
ZDHHC1	NP_037436.1	Mediates interaction with STING1. /evidence=ECO:0000269|PubMed:25299331	1..271		62/257 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41		2/2 (100%)
		DHHC	129..284	CDD:396215	40/173 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	324..358
		DPBB_RlpA_EXP_N-like	<362..>400	CDD:455124
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	462..485