DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18810 and Zdhhc19

DIOPT Version :9

Sequence 1:	NP_652670.2	Gene:	CG18810 / 59171	FlyBaseID:	FBgn0042133	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_955013.1	Gene:	Zdhhc19 / 245308	MGIID:	2682948	Length:	347	Species:	Mus musculus

Alignment Length:	294	Identity:	70/294 - (23%)
Similarity:	97/294 - (32%)	Gaps:	117/294 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LPELSDYWSPGYVF-----QLLL---GLF---------------------------LFSNVMSNY 68
            ||.:...|.|..||     .|||   |||                           .||.|..|:
Mouse    17 LPSIPLSWFPSSVFAAFNVTLLLFLSGLFFGFPCRWLVQNGEWAFPAITGPLFILTFFSLVSLNF 81

  Fly    69 VMCILVDPSIDPKLMKNQLVRGQHSED-----------------WHECDKCGILAPPRSRHCRKC 116
                 .||.|        |.||...||                 |  |.||....|||:.||..|
Mouse    82 -----SDPGI--------LHRGSTKEDPMTVHVVRVNQRAFRLEW--CPKCLFHRPPRTYHCPWC 131

  Fly   117 GVCVLMRDHHCFFTGCCIGHENYRYFFYFLIYFFL-------SCMISLTSSSIFIYVLHGGRYQL 174
            .:||...||||.:...||||.|:|.|...::...|       :|:..|..:....:.|..|  ..
Mouse   132 NICVEDFDHHCKWVNNCIGHRNFRLFMLLVLSLCLYSGALLVTCLTFLFRTRHLPFSLDKG--MA 194

  Fly   175 FMLTHPAPNSAYFNSLIIRIIYFKLPDIYELVFTLVFVLLWIGVCVATYV--AYDQWSRGYFCYD 237
            .::..||..             |.:|         :|:||.|.....:..  :|:...|.:..|:
Mouse   195 ILVAVPAAG-------------FLIP---------LFLLLLIQALSVSRAESSYESKCRYHPEYN 237

  Fly   238 FELQNIPFDRKLRRNFKTFLGRRMKWTWISGFVP 271
                  |||:...:|          | :::.|.|
Mouse   238 ------PFDQGFAKN----------W-YLAMFAP 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18810	NP_652670.2	zf-DHHC	92..>138	CDD:303066	22/62 (35%)
Zdhhc19	NP_955013.1	DHHC	109..>181	CDD:366691	26/73 (36%)
Zdhhc19	NP_955013.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	275..347
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810