DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18810 and dhhc-13

DIOPT Version :9

Sequence 1:	NP_652670.2	Gene:	CG18810 / 59171	FlyBaseID:	FBgn0042133	Length:	300	Species:	Drosophila melanogaster
Sequence 2:	NP_500889.2	Gene:	dhhc-13 / 186797	WormBaseID:	WBGene00019257	Length:	593	Species:	Caenorhabditis elegans

Alignment Length:	267	Identity:	65/267 - (24%)
Similarity:	98/267 - (36%)	Gaps:	78/267 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LFLFIL----------CGLPAIYYVLMEIILPELSDYWSPGYVFQLLL----GLFLFSNVMSNYV 69
            |.||||          | ||..|...|.|....|..:.|.|.|...:|    .:::.|  .|.|.
Worm   314 LLLFILVQRRQMDQFGC-LPVTYIFWMGIAEFALLIFNSNGLVHWSVLIFVCSIWVIS--ASFYW 375

  Fly    70 MCILVDPSIDPK-----------LMKNQLVRGQHSEDWHECDKCGILAPPRSRHCRKCGVCVLMR 123
            :.||.:|.:.|:           |.:.|:.|        .|..|.|.....|.||.:|..||...
Worm   376 ILILTNPGVLPRSTTPFKDFIKDLEEKQIDR--------YCFTCWIPKTSSSHHCSQCDKCVDGF 432

  Fly   124 DHHCFFTGCCIGHENYRYFFYFLIYFFLSCMISLTSSSIFIYVLHGGRYQLFMLTHPAPNSAYF- 187
            ||||.:...|:..:|.|.|.:|.:..|:        ..:| |||     .|..:...:.|::.|
Worm   433 DHHCPWIHKCVYRKNLRAFVFFCLTIFM--------FHVF-YVL-----LLLYMIGASMNASGFE 483

  Fly   188 -----NSLIIRIIYFKLPDIYELVFTLVFVLLWIGVCVATYVAYDQWSRGYFCYDFELQNIPFDR 247
                 :.|::..:...:|.::             |....|...:.|.||       .:..|...|
Worm   484 QTLNDHGLMVISLILAIPHVF-------------GAGAITCTQFSQISR-------HVSTIEIIR 528

  Fly   248 K--LRRN 252
            |  |:||
Worm   529 KQRLQRN 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18810	NP_652670.2	zf-DHHC	92..>138	CDD:303066	14/45 (31%)
dhhc-13	NP_500889.2	ANK	42..155	CDD:238125
		Ank_2	42..132	CDD:289560
		ANK repeat	67..98	CDD:293786
		ANK repeat	101..132	CDD:293786
		Ank_5	121..176	CDD:290568
		ANK	130..>240	CDD:238125
		Ank_5	198..243	CDD:290568
		ANK repeat	206..234	CDD:293786
		zf-DHHC	405..530	CDD:279823	36/166 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810