Protein Alignment CG18788 and SLC17A6

DIOPT Version :9

• Sequence 1: NP_652665.3
• Gene: CG18788 / 59164
• FlyBaseID: FBgn0042126
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_065079.1
• Gene: SLC17A6 / 57084
• HGNCID: 16703
• Length: 582
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 113/441 - (25%)
• Similarity: 190/441 - (43%)
• Gaps: 89/441 - (20%)

  Fly   135 WPRQTQSLVVMAFYAGYVLSHVPGGRLAERYGGKWVLSAAILTSAVLTLLTPTAVR--QGGLYAL 197
            |..:|..::..:|:.||:::.:|||.:|.|.....|..||||.::.|.:|.|:|.|  .|   .:
Human   119 WDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYG---CV 180

  Fly   198 VAVRLLVGICEGPCFPAVCALLAQWVPEQERGMLASCVLSGGEIGITMVQLVSGLLIAEQDWPVF 262
            :.||:|.|:.||..:||...:.::|.|..||..||:....|...|..:...::|:|:....|...
Human   181 IFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSV 245

  Fly   263 FYLVGGGAVAWFLGFTLVCYSTPDHCPFIQSEEREYIRCNTSNSFLLTTGREREEMDGEDGYEGE 327
            ||:.|...:.|::.:.||.|.:|...|.|..|||.||..:...|..|....|:.:
Human   246 FYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFK---------- 300

  Fly   328 DREHRREVEATCNTAPWRSMLNSTPLWALVSTSMQQEFQQKLPQELQIA-LEEVRARGTS----F 387
                          .|||....|.|::|::..:..:.:...|....|.| .|||.....|    .
Human   301 --------------TPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGML 351

  Fly   388 SELTTIIETIAPSVGNWIASLTTGRLSDVLIEQQILTRTQTRRLMSWLVFLCG------------ 440
            |.:..::.||...:|        |:::|.|..:|||:.|..|::|:     ||
Human   352 SAVPHLVMTIIVPIG--------GQIADFLRSKQILSTTTVRKIMN-----CGGFGMEATLLLVV 403

  Fly   441 ----------SMYMLQIKMSGARIWSVLGMGAYYASIKLLPLDMSPNYAGTLMGISGGMGALPAL 495
                      |..:|.:..||   :::.|....:       ||::|.||..|||||.|:|.|..:
Human   404 GYSHTRGVAISFLVLAVGFSG---FAISGFNVNH-------LDIAPRYASILMGISNGVGTLSGM 458

  Fly   496 LMPYL----------EQLETDYKLVSSVRAAMWVIGASYISGDVQAFNQPE 536
            :.|.:          |:.:..:.:.:.|.....:..|.:.||:.|.:..||
Human   459 VCPIIVGAMTKNKSREEWQYVFLIAALVHYGGVIFYAIFASGEKQPWADPE 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	129..>280	CDD:119392	44/146 (30%)
		MFS_1	135..498	CDD:284993	104/391 (27%)
SLC17A6	NP_065079.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	108/428 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820