DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18788 and slc17a8

DIOPT Version :9

Sequence 1:	NP_652665.3	Gene:	CG18788 / 59164	FlyBaseID:	FBgn0042126	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001076304.1	Gene:	slc17a8 / 563467	ZFINID:	ZDB-GENE-060503-416	Length:	590	Species:	Danio rerio

Alignment Length:	468	Identity:	120/468 - (25%)
Similarity:	199/468 - (42%)	Gaps:	83/468 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 EQPDLNQISAKGTRDREPAGEKRPGQEDSQERLSCSEQWPRQTQSLVVMAFYAGYVLSHVPGGRL 161
            |..:.|.:...||...:||                ...|..:|..|:..:|:.||:::.:|||.:
Zfish   102 EMVNNNTVYINGTAVMQPA----------------QFNWDPETVGLIHGSFFWGYIVTQIPGGFI 150

  Fly   162 AERYGGKWVLSAAILTSAVLTLLTPTAVRQGGLYALVA-VRLLVGICEGPCFPAVCALLAQWVPE 225
            :.:.....|..|||..::||.:..|:|.|..  |..|. ||:|.|:.||..:||...:.::|.|.
Zfish   151 SNKLAANRVFGAAIFLTSVLNMFIPSAARVH--YGCVMFVRILQGLVEGVTYPACHGMWSKWAPP 213

  Fly   226 QERGMLASCVLSGGEIGITMVQLVSGLLIAEQDWPVFFYLVGGGAVAWFLGFTLVCYSTPDHCPF 290
            .||..||:....|...|..:...::|:|:....||..||:.|...:.|::.:.|:.|::|...|.
Zfish   214 LERSRLATTSFCGSYAGAVIAMPLAGILVQYVGWPSVFYIYGVFGIIWYIFWILLAYNSPAVHPT 278

  Fly   291 IQSEEREYIRCNTSNSFLLTTGREREEMDGEDGYEGEDREHRREVEATCNTAPWRSMLNSTPLWA 355
            |..|||.||..:......|.:..|:.:                        .|||....|.|::|
Zfish   279 ISEEERNYIETSIGEGANLMSSTEKFK------------------------TPWREFFTSMPVYA 319

  Fly   356 LVSTSMQQEFQQKLPQELQIA-LEEVRARGTS----FSELTTIIETIAPSVGNWIASLTTGRLSD 415
            ::..:..:.:...|....|.| .|||.....|    .|.:..::.||...:|        |:|:|
Zfish   320 IIVANFCRSWTFYLLLISQPAYFEEVFGFPISKVGILSAVPHMVMTIIVPIG--------GQLAD 376

  Fly   416 VLIEQQILTRTQTRRLMSWLVFLCGSMYM-----LQIKMSGARIWSV------LGMGAYYAS-IK 468
            .|..::||:.|..|::|:     ||...|     |.:..|..|..::      :|...:..| ..
Zfish   377 FLRSRKILSTTTVRKIMN-----CGGFGMEATLLLVVGFSHTRAVAISFLILAVGFSGFAISGFN 436

  Fly   469 LLPLDMSPNYAGTLMGISGGMGALPALLMPYLEQLETDYK----------LVSSVRAAMWVIGAS 523
            :..||::|.||..|||||.|:|.|..::.|.:....|.:|          :.|.|.....:..|.
Zfish   437 VNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGALTKHKTRLEWQHVFVIASMVHYTGVIFYAI 501

  Fly   524 YISGDVQAFNQPE 536
            :.||:.|.:..||
Zfish   502 FASGEKQDWADPE 514

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	129..>280	CDD:119392	44/151 (29%)
CG18788	NP_652665.3	MFS_1	135..498	CDD:284993	103/380 (27%)
slc17a8	NP_001076304.1	2A0114euk	75..514	CDD:129972	118/466 (25%)
		MFS	81..503	CDD:119392	115/455 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	526..590
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820