DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18788 and MFS14

DIOPT Version :9

Sequence 1:	NP_652665.3	Gene:	CG18788 / 59164	FlyBaseID:	FBgn0042126	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001286591.1	Gene:	MFS14 / 46085	FlyBaseID:	FBgn0010651	Length:	497	Species:	Drosophila melanogaster

Alignment Length:	503	Identity:	129/503 - (25%)
Similarity:	206/503 - (40%)	Gaps:	137/503 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 WRIELAMAL-----NHTEYQLRSRLKAGKEQPDLNQISAKGTRDREPAGEKRPGQEDSQERLSCS 132
            ||:.|::||     |.|..          .|.:.|    .|....||..:           ...|
  Fly    40 WRVNLSVALVAMTDNSTSL----------AQNNTN----TGVAPSEPGFD-----------FFNS 79

  Fly   133 EQWPRQTQ---SLVVMAFYAGYVLSHVPGGRLAERYGGKWVLSAAILTSAVLTLLTPTAVRQGGL 194
            |::...||   ..:..:|:.||:::.||||.:|:|||.|.:|...:..:|::|:|:|.:: |.|.
  Fly    80 ERYYNFTQKEKGNLQASFFFGYIVTQVPGGYIAQRYGAKTMLMYGLGIAALITMLSPMSL-QFGW 143

  Fly   195 YALVAVRLLVGICEGPCFPAVCALLAQWVPEQERGMLASCVLSGGEIGITMVQLVSGLLIAEQ-- 257
            .||..:|.::|:.:|...||..||||:|.|..|||||.:...||.:.| |:|.|.:...||:.
  Fly   144 VALAVMRFVMGLAQGAVHPATHALLAKWSPADERGMLGTLCYSGAQFG-TVVMLATSGFIADSVL 207

  Fly   258 DWPVFFYLVGGGAVAWFLGFTLVCYSTPDHCPFIQSEEREYIRCNTSNSFLLTTGREREEMDGED 322
            .||..|||.|.....|.:.:.|...|||:....|...|.:||..:.|              ||:
  Fly   208 GWPSIFYLGGACGFIWMVFWYLFSASTPEEHRLISPGELKYITDSRS--------------DGK- 257

  Fly   323 GYEGEDREHRREVEATCNTAPWRSMLNSTPL--------------WAL---VSTSMQQEFQ---- 366
                     .:..|....| ||:::.:|.|.              |.|   :.|.|::.:.
  Fly   258 ---------MQSAEKLAPT-PWKAIFSSLPFLSLLVVHCTHIFGYWLLLMQIPTYMKKIYHVDIK 312

  Fly   367 -----QKLPQELQI-----------ALEEVRARGTSFSELTTIIETIAPSVGNWIASLTTGRLSD 415
                 ..||..:.:           .|::......||:      ..|..|:|:||..|:...|..
  Fly   313 KGALLSSLPYMVMLLLSFFFVWLSKVLQKKEGMSLSFN------RKIFNSIGHWIPMLSLIALGY 371

  Fly   416 VLIEQQILTRTQTRRLMSWLVFLCGSMYMLQIKMSGARIWSVLGMGAYYASIKLLPLDMSPNYAG 480
            |..:...|..|               :..|.:.:|||.          |...::..:|:||||||
  Fly   372 VPADNAPLAVT---------------LLTLTVGISGAT----------YLGFQVNHIDLSPNYAG 411

  Fly   481 TLMGISGGMGALPALLMPYL-------EQLETDYKLVSSVRAAMWVIG 521
            |||||:.....:.:.:.|.:       |...|:::||..:.||.:.:|
  Fly   412 TLMGITNCAANVMSGIAPVIVGQIVVDETSVTEWRLVFLLAAAFYFLG 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	129..>280	CDD:119392	56/155 (36%)
CG18788	NP_652665.3	MFS_1	135..498	CDD:284993	107/404 (26%)
MFS14	NP_001286591.1	2A0114euk	19..477	CDD:129972	129/503 (26%)
MFS14	NP_001286591.1	MFS	81..466	CDD:119392	115/437 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.970