DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18788 and CG7091

DIOPT Version :9

Sequence 1:	NP_652665.3	Gene:	CG18788 / 59164	FlyBaseID:	FBgn0042126	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_650243.2	Gene:	CG7091 / 41590	FlyBaseID:	FBgn0038099	Length:	509	Species:	Drosophila melanogaster

Alignment Length:	512	Identity:	116/512 - (22%)
Similarity:	199/512 - (38%)	Gaps:	118/512 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 VRQRWVLCCFTFLAIINAYTMRLCLDCT----LNRIILECGGHRVDNVPQVLNPKALPNWRIELA 78
            ||..:.:|.|          :..||...    |..|||           :::.|:  |...:.:.
  Fly    26 VRLTYAICAF----------LATCLHAAMRNMLGMIIL-----------KMVMPR--PEDALVVP 67

  Fly    79 MALNH-TEYQLRSRLKAGKEQPDLN-QISAKGTRDREPAGEKRPGQEDSQERLSCSEQWPRQTQS 141
            ..|:. ||..:.|..:.|..:...| ||                     ||..|....|.|..:.
  Fly    68 AGLSRLTEGNVTSTGRCGSPRVVFNPQI---------------------QETQSGDLPWTRNQEL 111

  Fly   142 LVVMAFYAGYVLSHVPGGRLAERYGGKWVLSAAILTSAVLTLLTPTAVR---QGGLYALVAVRLL 203
            .....:|.|||:|....|.||:|...|.:...:::..||..:|.|....   :.|:..||...||
  Fly   112 TFPGVYYYGYVVSISLSGYLADRCSSKRLFIVSLIFEAVAYILLPAMAHSSFEAGVVDLVICGLL 176

  Fly   204 VGICEGPCFPAVCALLAQWVPEQERGMLASCVLSGGEIGITMVQLVSGLLIAEQDWPVFFYLVGG 268
            .| |..   ||:..|...|....||..|.|...||..:|..:|..|:..| :...|.:.||:|||
  Fly   177 AG-CGN---PAMYKLFVTWAHPTERTALLSFAYSGLLMGSMLVYPVASYL-SNFGWELSFYVVGG 236

  Fly   269 GAVAWFLGFTLVCYSTPDHCPFIQSEEREYIRCNTSNSFLLTTGREREEMDGEDGYEGEDREHRR 333
            ..:::.:....:.|.|.:..|.|.:||.:|:|...|.     .|::|:.:
  Fly   237 VGLSFGIACCFLVYDTVEQHPRISNEEVDYLRQGKSQ-----LGQQRQPV--------------- 281

  Fly   334 EVEATCNTAPWRSMLNSTPLWALVSTSMQQEFQ-----QKLPQELQIALE-EVRARGTSFSELTT 392
                  .|.||:|:|.:.|::|.:.|.|...:.     |.:|:.::.|:| ::|..|
  Fly   282 ------VTIPWKSLLAAPPVYAFILTHMFHTYTFLVIVQLMPRFMREAMEFDLREVG-------- 332

  Fly   393 IIETIAPSVGNWIASLTTGRLSDVLIEQQI-------------LTRTQTRRLMSWLVFL-CGSMY 443
             ..:.||.:|. |.|.....|....:|:::             :....|..|:..::.. |....
  Fly   333 -FLSAAPYLGG-ICSKVMCILGGSYVERRVGPDQNCVRRMLYGICSILTTSLIGVIILANCDDKI 395

  Fly   444 MLQIKMSGARIWSVLGMGAYYASIKLLPLDMSPNYAGTLMGISGGMGALPALLMPYL 500
            ::.:..:.....:.:|...|:.::    |..:|::||.|.|::.||..|...|.|:|
  Fly   396 LVLVMFAFMMATTDMGFSGYWPTL----LYFAPSFAGLLSGLANGMAHLSGFLAPHL 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	129..>280	CDD:119392	44/153 (29%)
CG18788	NP_652665.3	MFS_1	135..498	CDD:284993	91/385 (24%)
CG7091	NP_650243.2	2A0114euk	77..498	CDD:129972	101/438 (23%)
CG7091	NP_650243.2	MFS	115..482	CDD:119392	91/379 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970