DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18788 and NaPi-T

DIOPT Version :9

Sequence 1:	NP_652665.3	Gene:	CG18788 / 59164	FlyBaseID:	FBgn0042126	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster

Alignment Length:	531	Identity:	108/531 - (20%)
Similarity:	189/531 - (35%)	Gaps:	155/531 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 EVRQRWVLCCFTFLAIINAYTMRLCLDCTLNRIILECGGHRVDNVPQVLNPKALPNWRIELAMAL 81
            :|..|.||...||:..|..|.:|:.|:.|:..:|...|                       |:..
  Fly     3 QVEARTVLWYMTFIGFIVNYMIRINLNITIVDMIAGKG-----------------------AITS 44

  Fly    82 NHTEYQLRSRLKAGKEQPDLNQISAKGTRDREPAGEKRPGQEDSQERLSCSE------------- 133
            |.|.          :...||..::                  :..||.|...
  Fly    45 NETH----------ENSTDLAALA------------------EMNERFSLERWFLDWANIPYEKN 81

  Fly   134 --QWPRQTQSLVVMAFYAGYVLSHVPGGRLAERYGGKWVLSAAILTSAVLTLLTPTAVRQGGLYA 196
              .|..:.|..::.:|:..:....:|||.||.:||.|.|...:.........|.| .|.......
  Fly    82 GFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGVFCCFLIP-IVSYWSYTG 145

  Fly   197 LVAVRLLVGICEGPCFPAVCALLAQWVPEQERGMLASCVLSGGEIGITMVQLVSGLLIAEQDWPV 261
            |:.:|:..|...|..:|::..|.|:|:|..||....|..| |..:|:.:...:.|.:|....|..
  Fly   146 LIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFVSAYL-GSSVGVALFYPIFGYIIDWTRWEW 209

  Fly   262 FFYLVGGGAVAWFLGFTLVCYSTPDHCPFIQSEEREYIRCNTSNSFLLTTGREREEMDGEDGYEG 326
            .:|:.|.....||:.:..:.:.:|...|.|...||::|..:...|
  Fly   210 VYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGAS-------------------- 254

  Fly   327 EDREHRREVEATCNTAPWRSMLNSTPLWALVSTSMQQEFQQKLPQELQIALEEVRARGTSFSELT 391
                    ::.:....||:::..|.|:|                      |..|...|..:...|
  Fly   255 --------IQGSKGPTPWKAIATSRPVW----------------------LNVVAQWGGIWGLFT 289

  Fly   392 TIIETIAPS----VGNWIASLTTGRLS------------------DVLIEQQILTRTQTRRLMSW 434
              :.|.||:    :.:|... .||.||                  |.|:....::||..|:|.::
  Fly   290 --LMTHAPTYFRLIHHWNIR-ATGFLSGLPHLMRMLFAYVFSIFADYLLRTDKMSRTNVRKLATF 351

  Fly   435 LVFLCGSMYMLQIKM------SGARIWSVLGMGAYYASIKLLPL----DMSPNYAGTLMGISGGM 489
            :  .||:..::.:.:      :.|.|..|......:.::...||    |:||||||.::|:||.:
  Fly   352 I--CCGTKGLIVLALAYFGYNATAAIVLVTVATMLHGAVSSGPLASMVDLSPNYAGIVLGVSGMI 414

  Fly   490 GALPALLMPYL 500
            |.:|..:.|::
  Fly   415 GGMPGFISPFI 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	129..>280	CDD:119392	38/165 (23%)
CG18788	NP_652665.3	MFS_1	135..498	CDD:284993	86/394 (22%)
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	108/531 (20%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	87/407 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.970