DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18788 and CG3036

DIOPT Version :9

Sequence 1:	NP_652665.3	Gene:	CG18788 / 59164	FlyBaseID:	FBgn0042126	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	556	Identity:	135/556 - (24%)
Similarity:	228/556 - (41%)	Gaps:	133/556 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 YLEVRQRWVLCCFTFLAIINAYTMRLCLDCTLNRIILECGGHRVD----NVPQVLNPKALPNWRI 75
            :|..||  ||...|.|..:..|.:|:.|...:           ||    ||...:|...:.|
  Fly    15 FLSCRQ--VLNLLTMLGFMLNYALRVNLTIAI-----------VDMVRPNVTSAVNATLVGN--- 63

  Fly    76 ELAMALNHTEYQLRSRLKAGKEQPDLNQISAKGTRDREPAGEKRPGQEDSQERLSCSEQWPRQTQ 140
              :.|.|.|            ..||                    |.:..:||.    .|.....
  Fly    64 --STAANST------------ASPD--------------------GVDVYEERF----PWDSYQT 90

  Fly   141 SLVVMAFYAGYVLSHVPGGRLAERYGGKWVLSAAILTSAVLTLLTPTAVRQGGLYALVAVRLLVG 205
            :.|:..|:.||:|:.:|||||||..||:.|...::|.:::|||:||.|... ....|:.||:::|
  Fly    91 NFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASLLTLITPLAAHI-NYVVLIVVRVVLG 154

  Fly   206 ICEGPCFPAVCALLAQWVPEQERGMLASCVLSGGEIGITMVQLVSGLLIAEQDWPVFFYLVGGGA 270
            ...|..:||:..:.|.|:|..||....|.::: ..:|..:...:.|.||:...|...|||.|...
  Fly   155 FMLGASWPAIHPVAAVWIPPMERSKFMSNMMA-SSLGAAITMPICGYLISVAGWASVFYLTGAVG 218

  Fly   271 VAWFLGFTLVCYSTPDHCPFIQSEEREYIRCNTSNSFLLTTGREREEMDGEDGYEGEDREHRREV 335
            :.|.|.:....|.||...|.|.:|||..|    ..:...||.::|.
  Fly   219 LLWSLAWFTFVYETPATHPRISAEERREI----EEAIGTTTSKKRP------------------- 260

  Fly   336 EATCNTAPWRSMLNSTPLWALVSTSMQQEF-----QQKLPQELQIALE-EVRARGTSFSELTTII 394
                :..||..:|.|..:||::.......|     ..:||..:...|. :::..|. ||.|
  Fly   261 ----SHVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQNGL-FSSL---- 316

  Fly   395 ETIAPSVGNWIASLTTGRLSDVLIEQQILTRTQTRRLM-SWLVFLCGSMYMLQIKMSGARIWSV- 457
                |.:|.::.::.:..|:|.|.::..|:.|.||:|. ::.:.:.|.:.::|:.:.....|||
  Fly   317 ----PYLGKYVMAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWSVT 377

  Fly   458 ------LGMGAYYASIKLLPLDMSPNYAGTLMGISGGMGALPALL-------MPYLEQLETDYKL 509
                  ...||..|......||::||:.||:.|::..:.:....|       :.|.:|....:::
  Fly   378 IFSLALFAHGAVTAGYLGNGLDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTYKDQSFHSWQI 442

  Fly   510 VSSVRAAMWVIGASYI----------SGDVQAFNQP 535
            |      .|::.|:||          ||::|.:|.|
  Fly   443 V------FWILAATYISAAVVFAILGSGELQPWNNP 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	129..>280	CDD:119392	47/150 (31%)
CG18788	NP_652665.3	MFS_1	135..498	CDD:284993	99/383 (26%)
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	134/552 (24%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	106/425 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.970