DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18788 and Slc17a4

DIOPT Version :9

Sequence 1:	NP_652665.3	Gene:	CG18788 / 59164	FlyBaseID:	FBgn0042126	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_795990.2	Gene:	Slc17a4 / 319848	MGIID:	2442850	Length:	492	Species:	Mus musculus

Alignment Length:	451	Identity:	117/451 - (25%)
Similarity:	200/451 - (44%)	Gaps:	82/451 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 NQISAKGTRDREPAGEKRPGQEDSQERLSCSEQWPRQTQSLVVMAFYAGYVLSHVPGGRLAERYG 166
            :|::|  :.:|.|...:....|..||..:....|..:.|.:::.:...|..::.:|.|.:|..:|
Mouse    69 SQLNA--STERPPTNSQDVWNETLQESKAPVYDWTPEIQGILLSSLSYGSFIAPIPTGYVAGVFG 131

  Fly   167 GKWVLSAAILTSAVLTLLTPTAVRQGGLYALVAVRLLVGICEGPCFPAVCALLAQWVPEQERGML 231
            .|:|:...:|.|:||||..|.|. ..|:..|:.:|::.|:.:........:|.|:|.|.|||..|
Mouse   132 AKYVVGLGLLISSVLTLFIPLAA-DAGVALLIVLRVIQGMAQVMVLTGQYSLWAKWAPPQERSQL 195

  Fly   232 ASCVLSGGEIGITMVQLVSGLLIAEQDWPVFFYLVGG-GAVAWFLGFTLVCYSTPDHCPFIQSEE 295
            .:...||..:|..:|.:..||:.....||..||:.|| |.....|.|.|| |..|.:.|||.:.|
Mouse   196 ITIAASGSMLGTFLVLIAGGLICQALGWPYIFYIFGGIGCACCLLWFPLV-YDDPQNHPFISTGE 259

  Fly   296 REYIRCNTSNSFLLTTGREREEMDGEDGYEGEDREHRREVEATCN---TAPWRSMLNSTPLWALV 357
            |.||.|:.:.                     ||          |:   :.|.::|:.|.||||:|
Mouse   260 RRYITCSLAQ---------------------ED----------CSLGWSLPIKAMVKSLPLWAIV 293

  Fly   358 ----------STSMQQEFQQKLPQELQIALE-EVRARGTSFSELTTIIETIAPSVGNWIASLTTG 411
                      ||.|..     .|..:...|: .:|..|         |.:..|.:...:..:..|
Mouse   294 VSYFCEYWLLSTVMAY-----TPTYISSVLQANLRDSG---------ILSALPFMFGCVCIILGG 344

  Fly   412 RLSDVLIEQQILTRTQTRRLMSWLVFLCGSMYMLQ---IKMSGARIWSVLGMGAYYASI----KL 469
            .|:|.|:.::||.....|:|.:.:..|..|..:|.   ::.|.:...:.|.:.:.:||:    .|
Mouse   345 LLADFLLSRKILRLVTIRKLFTAVGVLASSGILLPLPWVRSSRSTTMAFLVLSSVFASLCDSGAL 409

  Fly   470 LP-LDMSPNYAGTLMG-------ISGGMGALPALLMPYLEQ-LETDYKLVSSVRAAMWVIG 521
            :. ||::|.|||.|.|       ::||:.  |.:...::.| .|..::.|..:.||:.|:|
Mouse   410 INFLDIAPRYAGFLKGLLQVFSYLAGGIA--PTVAGFFISQDSEFGWRNVFFLAAAIDVVG 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	129..>280	CDD:119392	44/151 (29%)
CG18788	NP_652665.3	MFS_1	135..498	CDD:284993	103/392 (26%)
Slc17a4	NP_795990.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		2A0114euk	27..486	CDD:129972	117/451 (26%)
		MFS	98..475	CDD:119392	110/420 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D347586at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820