DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18788 and Slc17a2

DIOPT Version :9

Sequence 1:	NP_652665.3	Gene:	CG18788 / 59164	FlyBaseID:	FBgn0042126	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_038951630.1	Gene:	Slc17a2 / 306950	RGDID:	1308821	Length:	487	Species:	Rattus norvegicus

Alignment Length:	496	Identity:	127/496 - (25%)
Similarity:	207/496 - (41%)	Gaps:	98/496 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 RIELAMAL----NHTEYQLRSRLKAGKEQPDLNQISAKGTRDREPAGEKRPGQEDSQERLSCSEQ 134
            |:.|::|:    |.|::|  ....|..|.|.:|.:|   .|.|        |.:|...| :...|
  Rat    44 RVSLSIAIIAMVNSTQHQ--DPANASAEGPVMNLLS---NRSR--------GIKDFSTR-AAVYQ 94

  Fly   135 WPRQTQSLVVMAFYAGYVLSHVPGGRLAERYGGKWVLSAAILTSAVLTLLTPTAVRQGGLYALVA 199
            |..:||.::..:...|.:|:.:|.|.||..:|.|.:|.|.:|.|::|||.||.|. ..|:..::.
  Rat    95 WSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSLLTLFTPLAA-DFGVILVIV 158

  Fly   200 VRLLVGICEGPCFPAVCALLAQWVPEQERGMLASCVLSGGEIGITMVQLVSGLLIAEQDWPVFFY 264
            :|.:.|:.:|..:.....:.|:|.|..||..|.|...||...|..::..|.||:.....||..||
  Rat   159 IRTVQGMAQGMSWTGQFTIWAKWAPPLERSKLTSIAGSGAAFGSFIILCVGGLISQALGWPFIFY 223

  Fly   265 LVGG-GAVAWFLGFTLVCYSTPDHCPFIQSEEREYIRCNTSNSFLLTTGREREEMDGEDGYEGED 328
            :.|. |.|...|.||:: |..|.|.|.|..:|:|||..:.:.                     :.
  Rat   224 IFGSIGCVCCVLWFTMI-YDDPMHHPCISVKEKEYITSSVAQ---------------------QS 266

  Fly   329 REHRREVEATCNTAPWRSMLNSTPLWALVSTSMQQEFQ-----QKLPQELQIALE-EVRARGTSF 387
            ...||.:       |.::|:...||||:........:.     ..||..:...|. .:|..|. .
  Rat   267 SSPRRSI-------PIKAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDSGV-L 323

  Fly   388 SELTTIIETIAPSVGNWIASLTTGRLSDVLIEQQILTRTQTRRLMSWLVFLCGSMYMLQIKMSGA 452
            |.|..|..:....:|        |:::|.|:.:.:|:....|:|.|.|..|..|:..:.:...
  Rat   324 SSLPFIAASSCTILG--------GQMADFLLSRNLLSLITVRKLFSSLGLLLPSLCAVALPFV-- 378

  Fly   453 RIWSVLGMGAYYASIKLL-----------------PLDMSPNYAGTLMGISGGMGALPALLMP-- 498
                   ..:|.|:|.||                 .||::|.||..|||||.|.|....::..
  Rat   379 -------TSSYIATIVLLILIPGTSNLCDSGFIINTLDVAPRYASFLMGISRGFGLTAGIISSTT 436

  Fly   499 --YL--EQLETDYKLVSSVRAAMWVIGASY--ISGDVQAFN 533
              :|  :..|:.::.|..:.||:.:.|..:  |.|..:..|
  Rat   437 TGFLISQDSESGWRNVFFLSAAVNMFGLIFYLIFGQAEIQN 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	129..>280	CDD:119392	49/151 (32%)
CG18788	NP_652665.3	MFS_1	135..498	CDD:284993	101/386 (26%)
Slc17a2	XP_038951630.1	MFS_SLC17	30..471	CDD:340876	125/488 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D347586at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820