DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18788 and Slc17a2

DIOPT Version :9

Sequence 1:	NP_652665.3	Gene:	CG18788 / 59164	FlyBaseID:	FBgn0042126	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_006516709.1	Gene:	Slc17a2 / 218103	MGIID:	2443098	Length:	480	Species:	Mus musculus

Alignment Length:	491	Identity:	119/491 - (24%)
Similarity:	200/491 - (40%)	Gaps:	112/491 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 RIELAMAL----NHTEYQLRSRLKAGKEQPDLNQISAKGTRDREPAGEKRPGQEDSQERLSCSEQ 134
            |:.|::|:    |.|::|  ....|..|.|.::.:|           .:..|.:|...| :...|
Mouse    35 RVSLSIAIIAMVNSTQHQ--DPANASTEGPVMDLLS-----------NQSRGIKDFSTR-AAVYQ 85

  Fly   135 WPRQTQSLVVMAFYAGYVLSHVPGGRLAERYGGKWVLSAAILTSAVLTLLTPTAVRQGGLYALVA 199
            |..:||.::..:...|.:|:.:|.|.||..:|.|.:|.|.:|.|::|||.||.|. ..|:..::.
Mouse    86 WSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSLLTLFTPLAA-DFGVILVIV 149

  Fly   200 VRLLVGICEGPCFPAVCALLAQWVPEQERGMLASCVLSGGEIGITMVQ--------LVSGLLIAE 256
            :|.:.|:.:|..:.....:.|:|.|..||..|.|...||.::|...|.        .::|..:|
Mouse   150 IRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTSIAGSGEDVGSVWVLHHPLCGRINLTGTGLA- 213

  Fly   257 QDWPVFFYLVG--GGAVAWFLGFTLVCYSTPDHCPFIQSEEREYIRCNTSNSFLLTTGREREEMD 319
                  |||:.  .|.|...|.||:: |..|.|.|.|...|:|:|..:.:.
Mouse   214 ------FYLLHLCIGCVCCVLWFTVI-YDDPMHHPCISVREKEHITSSVAQ-------------- 257

  Fly   320 GEDGYEGEDREHRREVEATCNTAPWRSMLNSTPLWALVSTSMQQEFQ-----QKLPQELQIALE- 378
                   :....||.|       |.::|:...||||:........:.     ..||..:...|.
Mouse   258 -------QSSSPRRSV-------PIKAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHV 308

  Fly   379 EVRARGTSFSELTTIIETIAPSVGNWIASLTTGRLSDVLIEQQILTRTQTRRLMSWLVFLCGSMY 443
            .:|..|. .|.|..|..:....:|        |:::|.|:.:.:|:....|:|.|.|..|..|:.
Mouse   309 NIRDSGV-LSSLPFIAASSCTILG--------GQMADFLLSRNLLSLITVRKLFSSLGLLLPSLC 364

  Fly   444 MLQIKMSGARIWSVLGMGAYYASIKLL-----------------PLDMSPNYAGTLMGISGGMGA 491
            .:.:...         ..:|.|:|.||                 .||::|.||..|||||.|.|.
Mouse   365 AVALPFV---------TSSYIATIVLLILIPGTSNLCDSGFIINTLDVAPRYASFLMGISRGFGL 420

  Fly   492 LPALLMP----YL--EQLETDYKLVSSVRAAMWVIG 521
            ...::..    :|  :..|:.::.|..:.||:.:.|
Mouse   421 TAGIISSTTTGFLISQDSESGWRNVFFLSAAVNMFG 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	129..>280	CDD:119392	47/160 (29%)
CG18788	NP_652665.3	MFS_1	135..498	CDD:284993	99/395 (25%)
Slc17a2	XP_006516709.1	MFS_SLC17	21..464	CDD:340876	119/491 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D347586at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820