DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18788 and Slc17a8

DIOPT Version :9

Sequence 1:	NP_652665.3	Gene:	CG18788 / 59164	FlyBaseID:	FBgn0042126	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_892004.1	Gene:	Slc17a8 / 216227	MGIID:	3039629	Length:	601	Species:	Mus musculus

Alignment Length:	441	Identity:	108/441 - (24%)
Similarity:	187/441 - (42%)	Gaps:	90/441 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 WPRQTQSLVVMAFYAGYVLSHVPGGRLAERYGGKWVLSAAILTSAVLTLLTPTAVR--QGGLYAL 197
            |..:|..|:..:|:.||:::.:|||.::.::....|..|||..::.|.:..|:|.|  .|   .:
Mouse   137 WDPETVGLIHGSFFWGYIVTQIPGGFISNKFAASRVFGAAIFLTSTLNMFIPSAARVHYG---CV 198

  Fly   198 VAVRLLVGICEGPCFPAVCALLAQWVPEQERGMLASCVLSGGEIGITMVQLVSGLLIAEQDWPVF 262
            :.||:|.|:.||..:||...:.::|.|..||..||:....|...|..:...::|:|:....|...
Mouse   199 MGVRILQGLVEGVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQYIGWASV 263

  Fly   263 FYLVGGGAVAWFLGFTLVCYSTPDHCPFIQSEEREYIRCNTSNSFLLTTGREREEMDGEDGYEGE 327
            ||:.|...:.|::.:.|..|..|...|.|.:.||.||..:......|.:
Mouse   264 FYIYGMFGIIWYMFWLLQAYECPAAHPTISNAERTYIETSIGEGANLAS---------------- 312

  Fly   328 DREHRREVEATCNTAPWRSMLNSTPLWALVSTSMQQEFQQKLPQELQIA-LEEVRARGTS----F 387
                    .:..|| |||....|.|::|::..:..:.:...|....|.| .|||.....|    .
Mouse   313 --------LSKFNT-PWRRFFTSLPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFAISKVGLL 368

  Fly   388 SELTTIIETIAPSVGNWIASLTTGRLSDVLIEQQILTRTQTRRLMSWLVFLCG------------ 440
            |.:..::.||...:|        |:|:|.|..::|||.|..|::|:     ||
Mouse   369 SAVPHMVMTIVVPIG--------GQLADYLRSRKILTTTAVRKIMN-----CGGFGMEATLLLVV 420

  Fly   441 ----------SMYMLQIKMSGARIWSVLGMGAYYASIKLLPLDMSPNYAGTLMGISGGMGALPAL 495
                      |..:|.:..||   :::.|....:       ||::|.||..|||||.|:|.|..:
Mouse   421 GFSHTKGVAISFLVLAVGFSG---FAISGFNVNH-------LDIAPRYASILMGISNGVGTLSGM 475

  Fly   496 LMPYL----------EQLETDYKLVSSVRAAMWVIGASYISGDVQAFNQPE 536
            :.|.:          |:.:..:.:.:.|..:..:....:.||:.|.:..||
Mouse   476 VCPLIVGAMTKHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQDWADPE 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	129..>280	CDD:119392	41/146 (28%)
CG18788	NP_652665.3	MFS_1	135..498	CDD:284993	100/391 (26%)
Slc17a8	NP_892004.1	2A0114euk	88..526	CDD:129972	106/439 (24%)
		MFS	93..515	CDD:119392	103/428 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	576..601
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820