DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18788 and slc-17.1

DIOPT Version :9

Sequence 1:	NP_652665.3	Gene:	CG18788 / 59164	FlyBaseID:	FBgn0042126	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001041300.1	Gene:	slc-17.1 / 181777	WormBaseID:	WBGene00022647	Length:	479	Species:	Caenorhabditis elegans

Alignment Length:	501	Identity:	118/501 - (23%)
Similarity:	199/501 - (39%)	Gaps:	84/501 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 ECGGHRVD-NVPQVLNPKALPN--WR----IELAMALNHTE-YQLRSRLKAGKEQPDLNQISAKG 108
            ||..:..| |:.:.::.:||.:  |:    :.:...|.... |.:|:.|.....:
Worm    11 ECSKNDEDVNIRRAIDDEALESKRWKRRHVVAILALLGFANIYAMRANLSIAIVE---------- 65

  Fly   109 TRDREPAGEKRPGQEDSQERLSCSEQWPRQTQSLVVMAFYAGYVLSHVPGGRLAERYGGKWVLSA 173
                ..:|.:|.....:...|...|.|...||.:|:.:|:.||::|.:|||.||..:|.|.:..|
Worm    66 ----MTSGTERKVNGTTLHVLGDFENWTPMTQGVVLSSFFYGYIVSQLPGGYLAYTHGAKTIFFA 126

  Fly   174 AILTSAVLTLLTPTAVRQG-GLYALVAVRLLVGICEGPCFPAVCALLAQWVPEQERGMLASCVLS 237
            ....:||.|||||...|.| |:  ||..|.:.|:.||..:||:..:.::|.|..|:..||:...|
Worm   127 GTFGTAVFTLLTPPFARMGYGM--LVFARFMEGLLEGVTYPAMHVIWSRWAPPMEQTKLATFAFS 189

  Fly   238 GGEIGITMVQLVSGLLIAEQDWPVFFYLVGGGAVAWFLGFTLVCYSTPDHCPFIQSEEREYIRCN 302
            |...|..:...:|..|.....||:.|:..|...|.|.:.:....:..|:..|.|.:.|...::
Worm   190 GSYFGTVVAMPLSAYLGEHFGWPMIFWFFGALGVIWCMVWYKTVHDRPEDDPKISTSELALLQ-- 252

  Fly   303 TSNSFLLTTGREREEMDGEDGYEGEDREHRREVEATCNTAPWRSMLNSTPLWALVSTSMQQE--- 364
                                         |..|.......||..:|.|.|:||::.....|.
Worm   253 -----------------------------RDAVSQNHYIVPWAQILRSKPVWAVIVAHSAQNLGF 288

  Fly   365 --FQQKLPQELQ-IALEEVRARGTSFSELTTIIETIAPSVGNWIAS---LTTGRLSDVLIEQQIL 423
              ....||:.|: ||...|...|            ||.|:..::..   :|.|:|.|.|...:..
Worm   289 YIMLTNLPKMLKDIAGYNVEKAG------------IASSLPYFLMGFQIITGGQLCDYLRRDKHY 341

  Fly   424 TRTQTRRLMSWLVFLCGSMYMLQIKMSGARIWSVL------GMGAY-YASIKLLPLDMSPNYAGT 481
            .....|::...|.|:..|:::..:..:...:..||      |:|.. :....:..||::|.|||.
Worm   342 DTLFVRKMACALGFIGQSVFLFLVMTTSNSLLLVLFFSISIGLGGICWCGFSVNHLDLAPQYAGH 406

  Fly   482 LMGISGGMGALPALLMPYLEQLETDYKLVSSVRAAMWVIGASYISG 527
            ||..|.....:|.:..|.|.........:......|::|.::|:.|
Worm   407 LMATSNTFATIPGIFGPLLVGAIVQNGTIGEWNVIMYIIISAYLLG 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	129..>280	CDD:119392	52/151 (34%)
CG18788	NP_652665.3	MFS_1	135..498	CDD:284993	97/379 (26%)
slc-17.1	NP_001041300.1	MFS_SLC17	42..460	CDD:340876	111/470 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920