Protein Alignment CG18788 and slc-17.7

DIOPT Version :10

• Sequence 1: NP_652665.3
• Gene: CG18788 / 59164
• FlyBaseID: FBgn0042126
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_505399.1
• Gene: slc-17.7 / 179308
• WormBaseID: WBGene00022788
• Length: 506
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 111/563 - (19%)
• Similarity: 196/563 - (34%)
• Gaps: 163/563 - (28%)

  Fly    11 DIFIYLEVRQRWVLCCFTFLAI--INAYTMRLCLDCTLNRIILECGGHRVDNVPQVLNPKALPNW 73
            |::....||.|.|:.....|.|  :....:.:.:.|.||...|      .|..|.:    |..|.
 Worm     6 DLWSLRSVRLRVVIAIALALTIEGLMRSNLNMAIVCMLNSTAL------TDGKPMI----ASLNT 60

  Fly    74 RIELAMALNHTEYQLRSRLKAGKEQPDLNQISAKGTRDREPAGEKRPGQEDSQERLSCSEQWPRQ 138
            .||.|.       .|...|:.|:.:    .:..|||                       ..|..|
 Worm    61 SIEPAT-------PLCPLLQFGESK----VVEHKGT-----------------------IFWTSQ 91

  Fly   139 TQSLVVMAFYAG--------YVLSHVPGGRLAERYGGKWVLSAAILTSAVLTLLTPTAVRQG--G 193
            .::::..|||||        .||:...|...:..|||        :.:.|.|.|||....|.  |
 Worm    92 DRAIIFAAFYAGGLVATLASEVLNRYIGATRSVLYGG--------IANVVGTFLTPFVASQTNFG 148

  Fly   194 LYALVAVRLLVGICEGPCFPAVCALLAQWVPEQERGMLASCVLSGGEIGITMVQLVSG-LLIAEQ 257
            .:.::.:|.::|..:|..:|.:..|:|||.|..|:....:...:|.::.:.:....:. |.....
 Worm   149 TFPIILLRFVMGFGQGVLWPCMLVLIAQWFPVNEKSTALAIATTGNQLSVVIAMFATAELCQLPW 213

  Fly   258 DWPVFF--YLVGG--GAVAWFLGFTLVCYSTPDHC-PFIQSEEREYIRCNTSNSFLLTTGREREE 317
            .||:.|  |.|.|  ..:.|:    ::.|.:|.|. ..:..:|..||          ||.|.|..
 Worm   214 GWPMAFHVYAVCGIVMCIIWY----MMVYDSPCHADKKLSRDELHYI----------TTERVRLR 264

  Fly   318 MDGEDGYEGEDREHRREVEATCNTAPWRSMLNSTPLWALVSTSMQQEFQQKLPQELQIALEEVRA 382
                       .:|..          |.:::.|..:||:.::|....:              |..
 Worm   265 -----------PQHPN----------WMALMKSPVVWAIAASSFAHNY--------------VTV 294

  Fly   383 RGTSFSEL--TTIIETIAPSVGNWIASLTTGRLSDVLIEQQILTR------TQTRRLMSWL---- 435
            ...::..|  .|::.....|.|.|.|      |..||   |::::      .::.|...|.
 Worm   295 GTITYLPLYYKTVLNMSLTSNGLWSA------LPFVL---QLISKVFYAGMAESARKRDWSDINR 350

  Fly   436 ------------VFLC-GSMYMLQIKMSGARIWSV-LGM---GAYYASIKLLPLDMSPNYAGTLM 483
                        :.:| |.:.:......||.|:.: |.|   ..|........:.::|.....:.
 Worm   351 ITKFCNSSASFGIAICFGLLCLCDCSQRGAAIFLICLAMCFVSGYIPGYNTSAVTIAPGQTAAIA 415

  Fly   484 GISGGMGALPALLMPY------LEQLETDYKLVSSVRAAMWVI 520
            ..|...|.:.:.:.||      .:....::|:|.:|.||:.|:
 Worm   416 AFSRFWGQIASSVAPYHIGAYTKQGTADEWKIVFAVIAAICVV 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	134..522	CDD:475125	87/438 (20%)
slc-17.7	NP_505399.1	MFS	31..467	CDD:475125	104/538 (19%)