Protein Alignment CG18788 and SLC17A4

DIOPT Version :10

• Sequence 1: NP_652665.3
• Gene: CG18788 / 59164
• FlyBaseID: FBgn0042126
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_005486.1
• Gene: SLC17A4 / 10050
• HGNCID: 10932
• Length: 497
• Species: Homo sapiens
• Alignment Length: 494
• Identity: 118/494 - (23%)
• Similarity: 204/494 - (41%)
• Gaps: 98/494 - (19%)

  Fly    72 NWRIELAMALNHTEYQLRSRLKAGKEQPDLNQISAKGTRDREPAGEKRPGQEDSQ---------- 126
            |..|.:...:|:|         |...||:              |..:|| ..|||
Human    56 NLSIAIPAMVNNT---------APPSQPN--------------ASTERP-STDSQGYWNETLKEF 96

  Fly   127 ERLSCSEQWPRQTQSLVVMAFYAGYVLSHVPGGRLAERYGGKWVLSAAILTSAVLTLLTPTAVRQ 191
            :.::.:..|..:.|.:::.:...|..|:.:|.|.:|..:|.|:|:.|.:..|:.|||..|.|. .
Human    97 KAMAPAYDWSPEIQGIILSSLNYGSFLAPIPSGYVAGIFGAKYVVGAGLFISSFLTLFIPLAA-N 160

  Fly   192 GGLYALVAVRLLVGICEGPCFPAVCALLAQWVPEQERGMLASCVLSGGEIGITMVQLVSGLLIAE 256
            .|:..|:.:|::.||.:........::..:|.|..||..|.:...||..:|..:|.|..|||...
Human   161 AGVALLIVLRIVQGIAQVMVLTGQYSIWVKWAPPLERSQLTTIAGSGSMLGSFIVLLAGGLLCQT 225

  Fly   257 QDWPVFFYLVGG-GAVAWFLGFTLVCYSTPDHCPFIQSEEREYIRCNTSNSFLLTTGREREEMDG 320
            ..||..||:.|| |.....|.|.|: |..|.:.|||.:.|:.||.|:.:            :.|.
Human   226 IGWPYVFYIFGGIGCACCPLWFPLI-YDDPVNHPFISAGEKRYIVCSLA------------QQDC 277

  Fly   321 EDGYEGEDREHRREVEATCNTAPWRSMLNSTPLWALVSTSMQQ-----EFQQKLPQELQIALE-E 379
            ..|:                :.|.|:|:.|.||||::.:...:     ......|..:...|: .
Human   278 SPGW----------------SLPIRAMIKSLPLWAILVSYFCEYWLFYTIMAYTPTYISSVLQAN 326

  Fly   380 VRARGTSFSELTTIIETIAPSVGNWIASLTTGRLSDVLIEQQILTRTQTRRLMSWLVFLCGSMYM 444
            :|..|         |.:..|.|...|..:..|.|:|.|:.::||.....|:|.:.:..|..|:.:
Human   327 LRDSG---------ILSALPFVVGCICIILGGLLADFLLSRKILRLITIRKLFTAIGVLFPSVIL 382

  Fly   445 LQ---IKMSGARIWSVL----GMGAYYASIKLLP-LDMSPNYAGTLMGISGGMGALPALLMP--- 498
            :.   ::.|.:...:.|    .:.::..|..|:. ||::|.|.|.|.|:......:...:.|
Human   383 VSLPWVRSSHSMTMTFLVLSSAISSFCESGALVNFLDIAPRYTGFLKGLLQVFAHIAGAISPTAA 447

  Fly   499 --YLEQ-LETDYKLVSSVRAAMWVIGASY--ISG--DVQ 530
              ::.| .|..::.|..:.||:.:.|..:  |.|  |||
Human   448 GFFISQDSEFGWRNVFLLSAAVNISGLVFYLIFGRADVQ 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	134..522	CDD:475125	99/408 (24%)
SLC17A4	NP_005486.1	MFS_SLC17	40..481	CDD:340876	114/487 (23%)