DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18788 and slc17a7b

DIOPT Version :9

Sequence 1:	NP_652665.3	Gene:	CG18788 / 59164	FlyBaseID:	FBgn0042126	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	XP_009295917.2	Gene:	slc17a7b / 100331980	ZFINID:	ZDB-GENE-131125-32	Length:	585	Species:	Danio rerio

Alignment Length:	488	Identity:	121/488 - (24%)
Similarity:	204/488 - (41%)	Gaps:	102/488 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 LAMALNHTEYQLRSRLKAGKEQPDLNQISAKGTRDREPAGEKRPGQEDSQERLSCSEQWPRQTQS 141
            ::|..|||.|                       ||.:|...|            ....|..:|..
Zfish    88 VSMVNNHTVY-----------------------RDGKPYIVK------------AQFSWDPETVG 117

  Fly   142 LVVMAFYAGYVLSHVPGGRLAERYGGKWVLSAAILTSAVLTLLTPTAVRQGGLYALVAVRLLVGI 206
            ::..:|:.||:::.:|||.:.:::....|...|::::::|.::.|||.|. ....::.||:|.|:
Zfish   118 MIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAVVSTSILNMMIPTAARM-HFGCVILVRILQGL 181

  Fly   207 CEGPCFPAVCALLAQWVPEQERGMLASCVLSGGEIGITMVQLVSGLLIAEQDWPVFFYLVGGGAV 271
            .||..:||...:.|:|.|..||..||:....|...|..:...::|:|:....|...||:.|...|
Zfish   182 VEGVSYPACHGIWAKWAPPLERSRLATTAFCGSYAGAVIAMPLAGVLVQYSGWSSVFYVYGSFGV 246

  Fly   272 AWFLGFTLVCYSTPDHCPFIQSEEREYIRCNTSNSFLLTTGREREEMDGED-GYEGEDREHRREV 335
            .|:|.:.||.|.:|...|.|..|||:||                |:..||. |...
Zfish   247 CWYLFWILVSYESPAAHPTITPEERKYI----------------EDAIGESAGLVN--------- 286

  Fly   336 EATCNTAPWRSMLNSTPLWALVSTSMQQEFQQKLPQELQIA-LEEVRARGTS----FSELTTIIE 395
            ..|....|||....|.|::|::..:..:.:...|....|.| .|||.....|    .|.|..::.
Zfish   287 PLTKFNTPWRQFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFKFEISKVGILSALPHLVM 351

  Fly   396 TIAPSVGNWIASLTTGRLSDVLIEQQILTRTQTRRLMSWLVFLCG-----SMYMLQIKMSGAR-- 453
            ||...:|        |:|:|.|....::|.|..|:||:     ||     :.::|.:..|..:
Zfish   352 TIVVPIG--------GQLADYLRTHNLMTTTNVRKLMN-----CGGFGLEATFLLVVGFSHTKGV 403

  Fly   454 -----IWSVLGMGAYYASIKLLPLDMSPNYAGTLMGISGGMGALPALLMPYL----------EQL 503
                 :.:|...|...:...:..||::|.||..|||||.|:|.|..::.|.:          |:.
Zfish   404 AISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKNKTREEW 468

  Fly   504 ETDYKLVSSVRAAMWVIGASYISGDVQAFNQPE 536
            :..:.:.|.|.....:....:.||:.|.:.:||
Zfish   469 QYVFLIASLVHYGGVIFYGLFASGEKQPWAEPE 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18788	NP_652665.3	MFS	129..>280	CDD:119392	41/150 (27%)
CG18788	NP_652665.3	MFS_1	135..498	CDD:284993	103/380 (27%)
slc17a7b	XP_009295917.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820