DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18766 and MSANTD1

DIOPT Version :9

Sequence 1:	NP_001263007.1	Gene:	CG18766 / 59150	FlyBaseID:	FBgn0042111	Length:	308	Species:	Drosophila melanogaster
Sequence 2:	NP_001036155.1	Gene:	MSANTD1 / 345222	HGNCID:	33741	Length:	278	Species:	Homo sapiens

Alignment Length:	156	Identity:	38/156 - (24%)
Similarity:	72/156 - (46%)	Gaps:	11/156 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PYEKFNKKRRQWEDSGVLELIKLWKVCAYELRTIKRNGHLYVAMAKQLTSL-GVPVTALEVHFKV 65
            |..:.:::.|.|.|:.:..|:.:|:....||:..|||..:|..||.:|..: |......|:..|:
Human    35 PQAEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMASKLFEMTGERRLGEEIKIKI 99

  Fly    66 NNLTQRYRQEQKTFETTGIISTWKFYSQVDDVFKSLAAHTGYKDKRMTSASNTSSLPSTSE---- 126
            .|:|.:||:.:...::......|.:|..:|.:   ||......|.::..:....  ||||:
Human   100 TNMTFQYRKLKCMTDSESAPPDWPYYLAIDGI---LAKVPESCDGKLPDSQPPG--PSTSQTEAS 159

  Fly   127 -SPVWKNPMSQQEFNSNNTEGFYKTE 151
             ||..|:......:|..:.||.::.:
Human   160 LSPPAKSTPLYFPYNQCSYEGRFEDD 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18766	NP_001263007.1	Myb_DNA-bind_4	10..93	CDD:404682	23/83 (28%)
MSANTD1	NP_001036155.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27
		Myb_DNA-bind_4	44..125	CDD:316362	22/80 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	138..168		8/31 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156667
Domainoid	1	1.000	44	1.000	Domainoid score	I12323
eggNOG	1	0.900	-	-		E1_KOG4282
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008224
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22666
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5282
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.870