DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18765 and CG6908

DIOPT Version :9

Sequence 1:	NP_001097750.1	Gene:	CG18765 / 59149	FlyBaseID:	FBgn0042110	Length:	393	Species:	Drosophila melanogaster
Sequence 2:	NP_650105.1	Gene:	CG6908 / 41410	FlyBaseID:	FBgn0037936	Length:	449	Species:	Drosophila melanogaster

Alignment Length:	466	Identity:	116/466 - (24%)
Similarity:	199/466 - (42%)	Gaps:	113/466 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SSP--LLVTQQSQDAS-------------LPTWVEKKELEALV-KQISEFRKIESLRWKWETQLA 50
            |||  .|..||.|..:             :|.|:::::.|.:: :...:.:||:|.|       .
  Fly    18 SSPHAKLSKQQRQQVNDMVRETEDIAIEPIPAWLDQQKFEPILERDFPDLKKIKSFR-------L 75

  Fly    51 EPA-----------LCVHIQVLVADNKKRQVSYLIKSPETVPVGLKLPRTGD---------FSTE 95
            ||.           |..:.::.:.|..::.:||:.|.         ||.:|:         |..|
  Fly    76 EPTAGKGENYTTLLLRANFELELNDGSEQSISYMAKI---------LPNSGNRENVASWKVFYKE 131

  Fly    96 RHMFEVVLPALEELYQNSDRIVHFGPPVI--QAKLKSSHIYGDYILNKGYSVANGLKGLSVTAME 158
            |:.:...:|..|::|:::.:.:.|||...  |.:|....|..:.:..:|:...:...||.:...|
  Fly   132 RNTYGQYIPEFEQMYKDAGKKISFGPRYYESQIELDDELIVLEDLGKRGFRNVDRQNGLDIQHTE 196

  Fly   159 GVLSKLAAYHAGTAA-----------YIAKTPGKIRELPKLRENSKSDEETAELKS------LYQ 206
            ..|.|||.:||.:|.           |.......:..|.:||||        :||:      ||.
  Fly   197 ATLEKLAQFHAASAVRFELKGSYPEEYNQNLCSVVDSLKELREN--------QLKAYIDAFPLYD 253

  Fly   207 LRFHESLRSNDARQY----EDKVKSFQKYVKSGTEILDSKTSFNVILNGSCWPNNLLLQVDAFGN 267
                .|..:||.:.|    :|..:||...::.         .|.|:.:|..|.||::.|.|..|.
  Fly   254 ----ASHLTNDVQAYGSQADDMFQSFAPKIEG---------EFRVLNHGDAWCNNIMYQYDEAGK 305

  Fly   268 VKDTLFSGFHTAQYGPAVYDLFSSLLTAPA--EKSSRFDGYVKFYHDQLIENLNLLKFLGKKPSL 330
            :.:..|.....:::.....||...:|::..  .|.::||..:||||::|||:|.|||:....|||
  Fly   306 LAEVNFVDLQMSRFSSPAQDLLYLILSSTELDIKIAKFDYLIKFYHEKLIESLKLLKYPKPLPSL 370

  Fly   331 TDLQLDLLKYGHWAFETATEILPIVLSDFGNN-DIEELFRNPVFGEQIR--------------EL 380
            ..|...:..||.|.....:.:||:||.|.|:: :::.|......|::||              |:
  Fly   371 RSLHQSIFIYGDWILPIVSILLPLVLIDGGDDANMDSLMDGEGAGDKIRNNMFKNHRVIKHQKEI 435

  Fly   381 LPWMENRGYFE 391
            |||...||.||
  Fly   436 LPWAHRRGAFE 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18765	NP_001097750.1	PKc_like	56..323	CDD:304357	73/300 (24%)
CG6908	NP_650105.1	EcKinase	81..363	CDD:281023	74/311 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26787
OrthoDB	1	1.010	-	-		D343262at33208
OrthoFinder	1	1.000	-	-		FOG0000277
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.960