DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and zgc:153968

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001070924.1	Gene:	zgc:153968 / 768292	ZFINID:	ZDB-GENE-061027-211	Length:	301	Species:	Danio rerio

Alignment Length:	261	Identity:	77/261 - (29%)
Similarity:	123/261 - (47%)	Gaps:	37/261 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 CGQTTPVFRDRGAENAELNEYPWMVLLLYENRLSLI--------RYVLTAAHCVIGGYLTQNDLV 153
            ||:.....|..|.:.|....:||.|.:.|.....|:        .:||:||.|.  ..||.::||
Zfish    27 CGRAPLKPRIIGGQTAMAGSWPWQVSIHYIPTGGLLCGGTLINREWVLSAAQCF--QKLTASNLV 89

  Fly   154 LKSVRLGE-STTDCITSESRCPH-LDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQ 216
               |.||. ||.|        |: :.....|...|..:.|:  |.:||||||:|..||.:|..|:
Zfish    90 ---VHLGHLSTGD--------PNVIHNPASQIINHPKYDSA--TNKNDIALLKLSTPVSFTDYIK 141

  Fly   217 PICLLDAEFPL-QDLNLQISGWDPTKSSQTLITSTVKE-RNP----ADCLNRYPSFRSASQVCAG 275
            |:||..:...| :.....|:||....:..|...:|::| :.|    .||.:.|.|..:...:|||
Zfish   142 PVCLTASGSSLGKGAVSWITGWGSINTGGTQFPTTLQEVKIPVVSNGDCKSAYGSLITDGMICAG 206

  Fly   276 GQRKG-DTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339
            ....| ..|.|..|.|   ::.:..:::: .:||||:|:. |.....|||:|::..:..|||:.:
Zfish   207 PNEGGKGICMGDGGGP---LVHNSSEQWI-QSGIASFGRG-CAQPKNPGVFTRVSEYESWIKSQI 266

  Fly   340 A 340
            :
Zfish   267 S 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	74/246 (30%)
		Tryp_SPc	108..335	CDD:214473	71/243 (29%)
zgc:153968	NP_001070924.1	Tryp_SPc	35..262	CDD:214473	72/246 (29%)
zgc:153968	NP_001070924.1	Tryp_SPc	36..265	CDD:238113	74/248 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910