DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and Prss22

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_006524968.4	Gene:	Prss22 / 70835	MGIID:	1918085	Length:	365	Species:	Mus musculus

Alignment Length:	264	Identity:	80/264 - (30%)
Similarity:	120/264 - (45%)	Gaps:	42/264 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 CGQTTPVFRDRGAENAELNEYPWMVLLLYE------NRLSLIRYVLTAAHCVIGGYLTQNDL-VL 154
            ||:...:.|..|.|::...::||:|.:|..      ..|...|:|:|||||    :.:..|. .|
Mouse    99 CGKPQQLNRIVGGEDSMDAQWPWIVSILKNGSHHCAGSLLTNRWVVTAAHC----FKSNMDKPSL 159

  Fly   155 KSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPIC 219
            .||.||..........|:    .|.:.....|..::...||:. ||||:||:..::::::|.|||
Mouse   160 FSVLLGAWKLGSPGPRSQ----KVGIAWVLPHPRYSWKEGTHA-DIALVRLEHSIQFSERILPIC 219

  Fly   220 LLDAEFPL-QDLNLQISGWD------PTKSSQTLITSTVKERNPADCLNRYPSFRSASQ------ 271
            |.|:...| ...:..|:||.      |....|||....|...:...|.:.|  :|.|.|
Mouse   220 LPDSSVRLPPKTDCWIAGWGSIQDGVPLPHPQTLQKLKVPIIDSELCKSLY--WRGAGQEAITEG 282

  Fly   272 -VCAG---GQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFS 332
             :|||   |:|  |.|.|.||.|:|    ..||:...|.||.|:|:. |.....|||||.:....
Mouse   283 MLCAGYLEGER--DACLGDSGGPLM----CQVDDHWLLTGIISWGEG-CAERNRPGVYTSLLAHR 340

  Fly   333 EWIK 336
            .|::
Mouse   341 SWVQ 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	77/253 (30%)
		Tryp_SPc	108..335	CDD:214473	76/250 (30%)
Prss22	XP_006524968.4	Tryp_SPc	108..346	CDD:238113	77/255 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910