DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and zgc:123217

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001032480.1	Gene:	zgc:123217 / 641414	ZFINID:	ZDB-GENE-051113-188	Length:	326	Species:	Danio rerio

Alignment Length:	280	Identity:	84/280 - (30%)
Similarity:	119/280 - (42%)	Gaps:	59/280 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 NKQT---CGQTTPVFRDRGAENAELNEYPWMVLLLYENR------LSLIRYVLTAAHCVIGGYLT 148
            |.||   ||......|..|..:|....:||.|.:.|.||      |...::|:|||||:|
Zfish    21 NAQTTYECGVAPLNTRIVGGTDAPAGSWPWQVSIHYNNRHICGGTLIHSQWVMTAAHCII----- 80

  Fly   149 QNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTV--HQGFTSSGGTYRNDIALLRLQFPVRY 211
            ..::.:.::.||..|    .|.|.....:|:||..::  |..|.:|  ...|||:|::|..||.:
Zfish    81 NTNINVWTLYLGRQT----QSTSVANPNEVKVGIQSIIDHPSFNNS--LLNNDISLMKLSQPVNF 139

  Fly   212 TKKIQPICL-LDAEFPLQDLNLQISGWDPTKSSQTLITSTVKERNPAD---------------CL 260
            :..|:|||| .:........:...:||......|.|         ||.               |.
Zfish   140 SLYIRPICLAANNSIFYNGTSCWATGWGNIGKDQAL---------PAPQTLQQVQIPVVANSLCS 195

  Fly   261 NRYPSFRSAS----QVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFL-AGIASYGQQY-CYSA 319
            ..|.|..:|:    .:|||...|| ||.|.||.|.....||     |:: |||.|||... |...
Zfish   196 TEYESVNNATITPQMICAGKANKG-TCQGDSGGPFQCKQGS-----VWIQAGITSYGTSAGCAVG 254

  Fly   320 GIPGVYTKIGHFSEWIKANL 339
            ..|.||:::..|..|||.|:
Zfish   255 AYPDVYSRVSEFQSWIKMNV 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	77/259 (30%)
		Tryp_SPc	108..335	CDD:214473	74/256 (29%)
zgc:123217	NP_001032480.1	Tryp_SPc	36..270	CDD:214473	75/259 (29%)
zgc:123217	NP_001032480.1	Tryp_SPc	37..273	CDD:238113	77/261 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910