DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and prss27

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	272	Identity:	84/272 - (30%)
Similarity:	126/272 - (46%)	Gaps:	50/272 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 CGQTTPVFRDR--GAENAELNEYPWMVLLLYENRL----SLI--RYVLTAAHCVIGGYLTQN-DL 152
            |||  |.|.||  |..||...|:||.|.::|:|..    ||:  .:|::||||....|..:| .:
Frog   411 CGQ--PAFSDRIVGGNNAVFGEWPWQVSIVYQNSHICGGSLVSSNWVVSAAHCFPRSYKIENMQV 473

  Fly   153 VLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQP 217
            :|....|...|:|.:.         :.|.:...:..:|..|.:  .|||::.::.||.|:..|.|
Frog   474 LLGCFALMNLTSDAVI---------IRVKRVITYPLYTGEGSS--GDIAMVEMESPVTYSSYILP 527

  Fly   218 IC--LLDAEFPLQDLNLQISGWDPTKSSQTL--------ITSTVKERNPADCLNRYPS-FRSASQ 271
            ||  |.:.:||...: ..::||...:|..:|        :...:...:..|.:..|.| ...|:|
Frog   528 ICIPLTNEDFPSGKM-CWVTGWGNIQSDVSLSPPYPLQEVEVPLVNASSCDTMYHYNSDLNPATQ 591

  Fly   272 ------VCAG---GQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTK 327
                  :|||   ||:  |.|.|.||.|:....|:    :.||.||.|:|.. |.....||||||
Frog   592 LVHDDMICAGYPEGQK--DACQGDSGGPLACKSGN----YWFLTGIVSWGDG-CAQPNRPGVYTK 649

  Fly   328 IGHFSEWIKANL 339
            :..||.||...|
Frog   650 VSSFSSWINQYL 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	76/256 (30%)
		Tryp_SPc	108..335	CDD:214473	74/253 (29%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113	76/257 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910