DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and epsilonTry

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_525112.1	Gene:	epsilonTry / 49080	FlyBaseID:	FBgn0010425	Length:	256	Species:	Drosophila melanogaster

Alignment Length:	257	Identity:	70/257 - (27%)
Similarity:	107/257 - (41%)	Gaps:	67/257 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 GAENAELNEYPWMVLLLYENRLSLIRYVLTAAH-CVIGGYLTQNDLVLKSVRLGESTTDCITS-E 170
            |.....::.:|:.|        ||.||   .:| |  ||.:..:|:|:       :...|:.| |
  Fly    33 GGYETSIDAHPYQV--------SLQRY---GSHFC--GGSIYSHDIVI-------TAAHCLQSIE 77

  Fly   171 SRCPHLDVEVGQT--------------TVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLL 221
            ::  .|.:.||.|              ..|:|:.|.  |..||||::|::..:.:...|:.|.:.
  Fly    78 AK--DLKIRVGSTYWRSGGSVHSVRSFRNHEGYNSR--TMVNDIAIIRIESDLSFRSSIREIRIA 138

  Fly   222 DAEFPLQDLNLQISGWDPTKSSQTLITSTVKERNPADCLNRYPSFRSAS------------QVCA 274
            |:. |.:.....:|||..|:|.    .||:.:...|..|......|..|            .:||
  Fly   139 DSN-PREGATAVVSGWGTTESG----GSTIPDHLLAVDLEIIDVSRCRSDEFGYGKKIKDTMLCA 198

  Fly   275 GGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIK 336
            ....| |.|.|.||.|::    || |.   |.|:.|:|.. |.....||||..:.||.|||:
  Fly   199 YAPHK-DACQGDSGGPLV----SG-DR---LVGVVSWGYG-CGDVRYPGVYADVAHFHEWIE 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	70/257 (27%)
		Tryp_SPc	108..335	CDD:214473	68/254 (27%)
epsilonTry	NP_525112.1	Tryp_SPc	30..249	CDD:214473	68/254 (27%)
epsilonTry	NP_525112.1	Tryp_SPc	31..252	CDD:238113	70/257 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910