DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP012504

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_001231011.2	Gene:	AgaP_AGAP012504 / 4578496	VectorBaseID:	AGAP012504	Length:	839	Species:	Anopheles gambiae

Alignment Length:	232	Identity:	68/232 - (29%)
Similarity:	99/232 - (42%)	Gaps:	45/232 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 LLYENRLSLIRYVLTAAHCVIGGYLTQNDLVLKSV-RLGESTTDCITSESRCPHLD-VEVGQTTV 185
            |::||      ::||||||.     ..:|.|...| |:|:........:.....|. ||:.:...
Mosquito    53 LIWEN------FILTAAHCA-----ADDDNVPPDVARMGDINIYSDEDDEFAQQLKIVEIIRHPK 106

  Fly   186 HQGFTSSGGTYRN---DIALLRLQFPVRYTKKIQPICL-LDAE--FPLQDLNLQISGWDPT---- 240
            |:        |.:   ||||::|:..|.....:.|.|| ||.|  ||    .|..:||..|
Mosquito   107 HK--------YNSNYYDIALMKLERNVTLHDTVAPSCLWLDDEIRFP----ELLAAGWGRTGFDQ 159

  Fly   241 KSSQTLITSTVKERNPADCLNRYP-SFRSAS------QVCAGGQRKGDTCAGISGSPVMGIMGSG 298
            .:::||:...:.......|...|. ..|...      |.|||.: |.|||.|.||.|:...:...
Mosquito   160 NTTKTLLKVQLAPITNDKCSTHYQRGVRKLENGLMDHQFCAGDE-KMDTCPGDSGGPLHVKLFKE 223

  Fly   299 VDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWI 335
            .....||.|:.|:|:....:|  ||||.|:..|.:||
Mosquito   224 WKLIPFLVGVTSFGKACGLAA--PGVYVKVSKFGDWI 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	68/232 (29%)
		Tryp_SPc	108..335	CDD:214473	66/230 (29%)
AgaP_AGAP012504	XP_001231011.2	Tryp_SPc	22..261	CDD:238113	68/232 (29%)
		Tryp_SPc	22..258	CDD:214473	66/230 (29%)
		Trypsin	327..528	CDD:278516
		Tryp_SPc	333..>433	CDD:304450
		Tryp_SPc	611..836	CDD:304450
		Tryp_SPc	611..832	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910