DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP009216

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_001238238.1	Gene:	AgaP_AGAP009216 / 4578289	VectorBaseID:	AGAP009216	Length:	244	Species:	Anopheles gambiae

Alignment Length:	259	Identity:	77/259 - (29%)
Similarity:	103/259 - (39%)	Gaps:	52/259 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 AENAELNEYPWMVLLL-----YENRLSLI--RYVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDC 166
            |.|..|.:.||..||.     :....|||  |||||.|||:....:|...|..|         ||
Mosquito     8 ANNGTLGQLPWTALLKTSSGEFACAASLISERYVLTVAHCIKNRNVTFVQLRKK---------DC 63

  Fly   167 ITSESRC---PHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAE---- 224
             ..:..|   |. |:.|.:...|.||  |.....|||||:||...|.:...:.||||..|.
Mosquito    64 -DEQGVCTLAPQ-DIPVERAIAHDGF--SARRKLNDIALVRLAQNVSFNNDVLPICLPVAPEYQP 124

  Fly   225 -----FPLQDLNLQISGWD-PTKSSQTLITSTVKERNPADCLNRYPSF------RSASQVCAGGQ 277
                 |..:|      |.| .:.::.|:..:.|......:|.||....      ...|.:|....
Mosquito   125 AGSNYFTARD------GQDYASLNTDTISITEVHPLTTENCENRLQELIKRQHKIQESHICGYEA 183

  Fly   278 RKGDTCAGISGSPVMGI--MGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339
            ...|.||..:|.|::.:  .|..|..     |:.|||.|.|....:|.|||::..|..||..||
Mosquito   184 GSFDGCATSAGGPLVALDRFGRNVQH-----GVVSYGVQDCSLENVPSVYTRVESFINWILHNL 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	75/256 (29%)
		Tryp_SPc	108..335	CDD:214473	73/253 (29%)
AgaP_AGAP009216	XP_001238238.1	Tryp_SPc	14..238	CDD:214473	70/247 (28%)
AgaP_AGAP009216	XP_001238238.1	Tryp_SPc	14..238	CDD:238113	70/247 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920