DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CLIPA19

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_001237509.2	Gene:	CLIPA19 / 4577382	VectorBaseID:	AGAP003245	Length:	356	Species:	Anopheles gambiae

Alignment Length:	338	Identity:	94/338 - (27%)
Similarity:	153/338 - (45%)	Gaps:	61/338 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 KCTRLVSCSPLMNILRPRGMTQAEKDVFAHRQCGLDPNGHELLHMVYVCCPELGDVLPNKQTCG- 98
            ||...:.|.||     ||.:: .:.:...:.||    |..|.  ..::|||:...|||....||
Mosquito    46 KCIYFLDCKPL-----PRALS-TDLNFLKNSQC----NQKEA--PGFICCPDKRHVLPEPPHCGV 98

  Fly    99 ----QTTPVFRDRGAENAELNEYPWMVLLLYEN---------RLSLIR--YVLTAAHCVI---GG 145
                |.|      ||:..:.::|||..|:.||.         ..:||.  ::|||||||.   .|
Mosquito    99 RAATQLT------GAQLTQPDDYPWTALIEYEKPDGTTGFHCGGTLINQGHILTAAHCVSSLRAG 157

  Fly   146 YLTQNDLVLKSVRLGE----STTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQ 206
            :....      |.|||    |..||..:....|.::.:|.:..||.|:.:..|::.:||||:|.:
Mosquito   158 WKVHR------VLLGEWDLSSVLDCAYNVCNNPPIEAKVSKIIVHDGYDAQNGSFNHDIALIRFE 216

  Fly   207 FPVRYTKKIQPICLLDAE-FPLQDLN---LQISGWDPTKSSQTL---ITSTVKERNPADC--LNR 262
            ....:...|.||||..|: .|.:::.   ..:.||..::|:..:   :...:|.||..:|  |..
Mosquito   217 ELANFPDTIVPICLPIADSIPWENITDGFSTVVGWGKSQSTAGVTKKLKLNLKVRNFRECSSLLE 281

  Fly   263 YPSFRSASQVCAGGQRKG-DTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYT 326
            :|.....||:||..:|.. ..|:..:|    |.:......|.:|.|:|...:|.|.|..:|||:.
Mosquito   282 WPEKMQPSQLCALWERSNRKICSADAG----GGLAWFYRRFHYLIGVAGSDEQKCGSGDVPGVFV 342

  Fly   327 KIGHFSEWIKANL 339
            .:.::..||:.|:
Mosquito   343 NVSYYMNWIRDNI 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	11/48 (23%)
		Tryp_SPc	108..338	CDD:238113	72/257 (28%)
		Tryp_SPc	108..335	CDD:214473	70/254 (28%)
CLIPA19	XP_001237509.2	CLIP	37..84	CDD:197829	12/49 (24%)
		Tryp_SPc	106..354	CDD:238113	72/257 (28%)
		Tryp_SPc	106..351	CDD:214473	70/254 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.880