DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CG10232

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_651175.4	Gene:	CG10232 / 42800	FlyBaseID:	FBgn0039108	Length:	509	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	150/393 - (38%)
Similarity:	198/393 - (50%)	Gaps:	65/393 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RRKVYILVLLQAIFFNQLAECVR-----------------------------------LSSCQKD 33
            ||:||:....|.||..|..|..|                                   ...|..|
  Fly   127 RRRVYVNCQRQEIFPCQYDEICRSRDSCPFLKLKRKKAQNILMSRQCGINTYCCPKQEFPDCPAD 191

  Fly    34 EKCTRLVSCSPLMNILRPRGMTQAEKDVFAHRQCGLDPNGHELLHMVYVCCPELGDVLPNKQTCG 98
            |||.||..|..:.|.....|     .::..:|||.:|....:.....|:||||.|:|||.  :||
  Fly   192 EKCIRLDKCLRIHNTTMEDG-----ANLMDNRQCAIDTRRIDSDKRHYICCPEPGNVLPT--SCG 249

  Fly    99 QTTPVFRDRGAENAELNEYPWMVLLLYENRL----------SLI--RYVLTAAHCVIGGYLTQND 151
            |..|::|......|..||||||.:|:||||.          |||  ||||||||||:...:...|
  Fly   250 QAPPLYRMAYGTAARPNEYPWMAMLIYENRRLSTMTNNCSGSLINKRYVLTAAHCVVKDKMVNTD 314

  Fly   152 LVLKSVRLGE----STTDC-ITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRY 211
            |||:.|||||    :..|| .|.....|.:::.:....||:.:.:: ..:.:||||:|||.||||
  Fly   315 LVLRRVRLGEHDITTNPDCDFTGNCAAPFVEIGIEYFNVHEQYFNT-SRFESDIALVRLQTPVRY 378

  Fly   212 TKKIQPICLLDAEFPLQDLNLQISGWDPTKS---SQTLITSTVKERNPADCLNRYPSFRSASQVC 273
            |.:|.|||:.....||.:..|||:||..||:   ||.|:.:||.| |...|.::...||:.||:|
  Fly   379 THEILPICVPKDPIPLHNHPLQIAGWGYTKNREYSQVLLHNTVYE-NRYYCQDKISFFRNESQIC 442

  Fly   274 AGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKAN 338
            |.|.|..|:|.|.||.|:|..:.:...:.|:||||.|||.:.|.... ||||||.|.|..|||||
  Fly   443 ASGIRGEDSCEGDSGGPLMLTLNNDYQDIVYLAGIVSYGSENCGDRK-PGVYTKTGAFFSWIKAN 506

  Fly   339 LAP 341
            |.|
  Fly   507 LKP 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	12/48 (25%)
		Tryp_SPc	108..338	CDD:238113	108/249 (43%)
		Tryp_SPc	108..335	CDD:214473	105/246 (43%)
CG10232	NP_651175.4	Tryp_SPc	260..506	CDD:238113	108/248 (44%)
CG10232	NP_651175.4	Tryp_SPc	260..503	CDD:214473	105/245 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463186
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	1	1.000	-	-		FOG0003849
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950