DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CG4053

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_650601.2	Gene:	CG4053 / 42070	FlyBaseID:	FBgn0038482	Length:	265	Species:	Drosophila melanogaster

Alignment Length:	258	Identity:	60/258 - (23%)
Similarity:	101/258 - (39%)	Gaps:	69/258 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 GAENAELNEYPWMV-------------LLLYENRLSLIRYVLTAAHCVIGGYLTQNDLVLKSVRL 159
            |.:.||....|:.|             ::|.|      :::|||.||.:       |..::.:|:
  Fly    37 GGQEAEDGVAPYQVSIQTIWKTHICSGVILNE------QWILTAGHCAL-------DFSIEDLRI 88

  Fly   160 GESTTDCITSESRCPHLDVEVGQT------TVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPI 218
            ...|.|           .:|.|||      .||..: .....|.|||||:.:...:.:..:.| |
  Fly    89 IVGTND-----------RLEPGQTLFPDEALVHCLY-DIPYVYNNDIALIHVNESIIFNDRTQ-I 140

  Fly   219 CLLDAEFPLQDLNLQISGWDPTKSS-------QTLITSTVKERNPADCLNRYPSFRSA---SQVC 273
            ..|..|.|.....:.::||...:||       |||..:.:...   :|..|: .|...   ..:|
  Fly   141 VELSREQPPAGSTVTLTGWGAPESSYPTVQYLQTLNLTIIAHE---ECRERW-DFHDGIDIGHIC 201

  Fly   274 AGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIK 336
            ...:.....|:|.||.|   :|..|.     |.|:.::|:. | ..|:|.:|....::.:||:
  Fly   202 TFTREGEGACSGDSGGP---LMWEGK-----LVGLVNWGRA-C-GVGMPDMYANTVYYQDWIR 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	60/258 (23%)
		Tryp_SPc	108..335	CDD:214473	58/255 (23%)
CG4053	NP_650601.2	Tryp_SPc	34..253	CDD:214473	58/255 (23%)
CG4053	NP_650601.2	Tryp_SPc	35..256	CDD:238113	60/258 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100