DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CG17475

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001287372.1	Gene:	CG17475 / 42069	FlyBaseID:	FBgn0038481	Length:	288	Species:	Drosophila melanogaster

Alignment Length:	265	Identity:	73/265 - (27%)
Similarity:	116/265 - (43%)	Gaps:	66/265 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 FRDR--GAENAELNEYPWMVLL--LYENRL---SLI--RYVLTAAHCVIGGYLTQNDLVLKSVRL 159
            |::|  ..|:.:|.|..:.:.|  :|...:   .:|  |:||||||||.|    .|...|: |..
  Fly    46 FQNRVINGEDVQLGEAKYQISLQGMYGGHICGGCIIDERHVLTAAHCVYG----YNPTYLR-VIT 105

  Fly   160 GESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAE 224
            |       |.|...|.....|.:..:|..:.|.  .|.|||||:||...:::.:..||     ||
  Fly   106 G-------TVEYEKPDAVYFVEEHWIHCNYNSP--DYHNDIALIRLNDTIKFNEYTQP-----AE 156

  Fly   225 FPLQDL----NLQISGWDPT-----------KSSQT-LITSTVKERNPADCLNRYPSFRSASQVC 273
            .|...:    .|.::||..|           |:..| ::.||.:|     .:|..|| .....:|
  Fly   157 LPTAPVANGTQLLLTGWGSTELWGDTPDILQKAYLTHVVYSTCQE-----IMNNDPS-NGPCHIC 215

  Fly   274 ---AGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWI 335
               .|||   ..|.|.||.|   :..:||     |.|:.::|  |..:.|:|..:..:.::.|||
  Fly   216 TLTTGGQ---GACHGDSGGP---LTHNGV-----LYGLVNWG--YPCALGVPDSHANVYYYLEWI 267

  Fly   336 KANLA 340
            ::.::
  Fly   268 RSMIS 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	71/255 (28%)
		Tryp_SPc	108..335	CDD:214473	69/252 (27%)
CG17475	NP_001287372.1	Tryp_SPc	49..267	CDD:214473	70/255 (27%)
CG17475	NP_001287372.1	Tryp_SPc	50..269	CDD:238113	71/256 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437211
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940