DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CG3505

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_650380.2	Gene:	CG3505 / 41777	FlyBaseID:	FBgn0038250	Length:	360	Species:	Drosophila melanogaster

Alignment Length:	371	Identity:	105/371 - (28%)
Similarity:	170/371 - (45%)	Gaps:	59/371 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ILVLLQAIFFNQLAE-----CV-RLSSCQKDEKCTRLVSCSPLMNILRPRGMTQAEKDVFAHRQC 67
            :||::.::.....|:     || ::.|.:....|..:..|...|.||....::|:::::....||
  Fly     7 LLVVVGSLALGANAQLPPINCVAKIPSGRVTGHCISIRECDYFMRILLSGNLSQSDRNLLRDNQC 71

  Fly    68 GLDPNGHELLHMVYVCCPE---LG----DVLPNKQTCGQTTPVFRDRGAENAELNEYPWMVLLLY 125
            |:..|.      |.||||.   ||    .:||:  .||:..  ::.....:..:.|:||:.|:.|
  Fly    72 GVRGND------VQVCCPSTAGLGALTHPLLPS--DCGKVR--WQRSNDTDTRIREFPWLALIEY 126

  Fly   126 ENR-----------LSLIRYVLTAAHCVIGGYLTQNDLVLKSVRLGESTT----DCITSE----S 171
            ...           |...||||||||||  .....::|.:.:|||||..|    ||...|    :
  Fly   127 TRGNQEKIHACGGVLISDRYVLTAAHCV--AQAATSNLQITAVRLGEWDTSTNPDCQYHEDSKVA 189

  Fly   172 RC--PHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEF---PLQDLN 231
            .|  |:.|:.:.:...|..:..:..|..|||||:||..|.:....:|||||.:.:.   .|:||.
  Fly   190 DCAPPYQDIAIEELLPHPLYNRTDRTQINDIALVRLASPAKLNDFVQPICLPNKQLRADELEDLV 254

  Fly   232 LQISGWDPTKSSQTLITSTVKERNPADCLNRYPSFR---SASQVCAGGQRKGDTCAGISGSPVMG 293
            .:::||. ..|||.:....|...:..:|..:|.|.:   .||::|  |......|.|.:|.|:|.
  Fly   255 TEVAGWQ-ASSSQRMRKGYVTISSIEECQRKYASQQLRIQASKLC--GLTNSQECYGNAGGPLML 316

  Fly   294 IMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339
            ....|    ..|.|:.|:|...|.:...|.|||::..:.:||..:|
  Fly   317 FKNDG----YLLGGLVSFGPVPCPNPDWPDVYTRVASYIDWIHDSL 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	12/48 (25%)
		Tryp_SPc	108..338	CDD:238113	77/256 (30%)
		Tryp_SPc	108..335	CDD:214473	75/253 (30%)
CG3505	NP_650380.2	CLIP	30..82	CDD:288855	13/57 (23%)
		Tryp_SPc	111..356	CDD:238113	77/253 (30%)
		Tryp_SPc	111..354	CDD:214473	75/251 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463216
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	1	1.000	-	-		FOG0003849
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950