DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18754 and LPA

DIOPT Version :9

Sequence 1:NP_652652.3 Gene:CG18754 / 59145 FlyBaseID:FBgn0042106 Length:341 Species:Drosophila melanogaster
Sequence 2:NP_005568.2 Gene:LPA / 4018 HGNCID:6667 Length:2040 Species:Homo sapiens


Alignment Length:240 Identity:68/240 - (28%)
Similarity:102/240 - (42%) Gaps:46/240 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   112 AELNEYPWMVLLLYENRL-------SLI--RYVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCI 167
            |..:.:||.|.|  ..|.       :||  .:|||||||           :.||.|  .|:...|
Human  1826 AHPHSWPWQVSL--RTRFGKHFCGGTLISPEWVLTAAHC-----------LKKSSR--PSSYKVI 1875

  Fly   168 TSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEFPL-QDLN 231
            ....:..:|:..|.:..|.:.|..   ..:.|||||:|..|...|.|:.|.||...::.: ....
Human  1876 LGAHQEVNLESHVQEIEVSRLFLE---PTQADIALLKLSRPAVITDKVMPACLPSPDYMVTARTE 1937

  Fly   232 LQISGWDPTKSSQTLITSTVKERN----PADCLNRYPSFRSASQVCAGGQRKG-DTCAGISGSPV 291
            ..|:||..|:.  |..|..:||..    ..:..|.|      ..:||....:| |:|.|.||.|:
Human  1938 CYITGWGETQG--TFGTGLLKEAQLLVIENEVCNHY------KYICAEHLARGTDSCQGDSGGPL 1994

  Fly   292 MGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIK 336
            :..   ..|::: |.|:.|:|.. |.....||||.::..|..||:
Human  1995 VCF---EKDKYI-LQGVTSWGLG-CARPNKPGVYARVSRFVTWIE 2034

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18754NP_652652.3 CLIP 35..84 CDD:288855
Tryp_SPc 108..338 CDD:238113 68/240 (28%)
Tryp_SPc 108..335 CDD:214473 66/237 (28%)
LPANP_005568.2 Kringle 28..105 CDD:278480
Kringle 142..219 CDD:278480
Kringle 256..333 CDD:278480
Kringle 370..447 CDD:278480
Kringle 484..561 CDD:278480
Kringle 598..675 CDD:278480
Kringle 712..789 CDD:278480
Kringle 826..903 CDD:278480
KR 938..1019 CDD:214527
Kringle 1054..1131 CDD:278480
KR 1166..1246 CDD:214527
KR 1272..1352 CDD:214527
KR 1386..1466 CDD:214527
KR 1500..1581 CDD:214527
KR 1614..1695 CDD:214527
Kringle 1720..1799 CDD:278480
Tryp_SPc 1820..2034 CDD:238113 67/238 (28%)
Tryp_SPc 1820..2033 CDD:214473 66/237 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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