DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CG11529

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_648558.1	Gene:	CG11529 / 39395	FlyBaseID:	FBgn0036264	Length:	287	Species:	Drosophila melanogaster

Alignment Length:	257	Identity:	69/257 - (26%)
Similarity:	112/257 - (43%)	Gaps:	66/257 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 LNEYPWMVLL----LYENRL----SLI--RYVLTAAHCVIGGYLTQNDLVL--KSVRLGESTTDC 166
            :.::|:.|:|    |:..|:    :|:  |::|||.||.:|  :|..|:.|  |||.
  Fly    38 IEKFPYQVMLIGKQLWRKRILCGGTLLDKRWILTAGHCTMG--VTHYDVYLGTKSVE-------- 92

  Fly   167 ITSESRCPHLDVEV--------GQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDA 223
                      |.||        .:..||:.|...  |..|||||::|...|.:|.:|||     |
  Fly    93 ----------DTEVSGGLVLRSNKFIVHERFNPE--TAANDIALVKLPQDVAFTPRIQP-----A 140

  Fly   224 EFP-------LQDLNLQISGW----DPTKSSQTLITSTVKERNPADCLNRYPSFRSASQVCAGGQ 277
            ..|       ...:::..|||    :.|.|.....|. :|..:.|:|...|....| ..:||.|.
  Fly   141 SLPSRYRHDQFAGMSVVASGWGAMVEMTNSDSMQYTE-LKVISNAECAQEYDVVTS-GVICAKGL 203

  Fly   278 RKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANL 339
            :....|.|.||.|::      :.:...:.||.|:|........|||.:|::.|:.:||::.:
  Fly   204 KDETVCTGDSGGPLV------LKDTQIVVGITSFGPADGCETNIPGGFTRVTHYLDWIESKI 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	69/254 (27%)
		Tryp_SPc	108..335	CDD:214473	67/251 (27%)
CG11529	NP_648558.1	Tryp_SPc	37..258	CDD:238113	69/254 (27%)
CG11529	NP_648558.1	Tryp_SPc	37..255	CDD:214473	67/251 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010