DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CG33460

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001033949.1	Gene:	CG33460 / 3885588	FlyBaseID:	FBgn0053460	Length:	275	Species:	Drosophila melanogaster

Alignment Length:	243	Identity:	65/243 - (26%)
Similarity:	99/243 - (40%)	Gaps:	60/243 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 PWMVLLLYENRL----SLIR--YVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCITSESRCP-- 174
            ||..||..:..:    :||.  ::||||.|:....:        .|||||.        .|.|
  Fly    44 PWTALLHTDGSIFCAGTLITDVFILTAASCIRPNAV--------KVRLGEF--------GRYPNE 92

  Fly   175 ----HLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDLNLQIS 235
                ||   |....:::.|.:.  :..|:|.||:|...|:.|..|.|:|::     |...|.|:|
  Fly    93 LPEDHL---VHYFLMYRLFNNE--SLANNIGLLKLTKRVQITDYIMPVCIV-----LNPQNQQLS 147

  Fly   236 -------GW--DPTKSSQTLITSTVKERNPADCLNRYPSFRSASQVCAGGQRKGDTCAGISGSPV 291
                   .|  |...|....:...|.:..|..|.|    ....:|.|||.|....:|.|::||.:
  Fly   148 TMRFIGNAWMEDSNVSLTKELRPIVIQSKPKMCTN----LDLYTQFCAGHQGNLRSCDGLTGSAL 208

  Fly   292 MGIMGSG-VDEFVFLA-GIASYGQQYC-YSAGIPGVYTKIGHFSEWIK 336
              |..|. ::::..:. |||:.....| .|.|    ||.:..|..||:
  Fly   209 --IQNSRYMNKYRHIQFGIATVNDMDCEESQG----YTDVLKFYWWIQ 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	65/243 (27%)
		Tryp_SPc	108..335	CDD:214473	63/240 (26%)
CG33460	NP_001033949.1	Tryp_SPc	44..252	CDD:304450	65/243 (27%)
CG33460	NP_001033949.1	Tryp_SPc	44..249	CDD:214473	63/240 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463511
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030