DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CG33465

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001033950.2	Gene:	CG33465 / 3885587	FlyBaseID:	FBgn0053465	Length:	488	Species:	Drosophila melanogaster

Alignment Length:	291	Identity:	74/291 - (25%)
Similarity:	101/291 - (34%)	Gaps:	79/291 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 VCCPELGDVLPNKQTCGQTTPVFRDRGAENAELNE-----YPWMVLLLYENRL----SLIR--YV 135
            |.|..|..:|..|  |..      .:.:||...|.     .|||..:...|:.    :|:.  :|
  Fly    13 VLCQGLAQLLDKK--CHD------PKTSENINFNHGATETAPWMASIYKNNQFICDGTLVHKLFV 69

  Fly   136 LTAAHCV---------IGGYLTQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTS 191
            ||||.|:         .|.|....|           .:....:|      ...|.....|..|..
  Fly    70 LTAASCISKDSQLYVLFGMYNQYRD-----------ASQFFNNE------QYGVAVALQHSNFRP 117

  Fly   192 SGGTYRNDIALLRLQFPVRYTKKIQPICLL------DAEFPLQDLNLQISGWD---PTKSSQTLI 247
            :.|.  |||.||||...|.:...|:|||::      .|.|.    ..:..||.   ...|||...
  Fly   118 NNGV--NDIGLLRLYGEVTHYAHIRPICIILDHVVKSAPFE----RFEGFGWQQQGTEASSQVRQ 176

  Fly   248 TSTVKERNPADC--------LNRYPSFRSASQVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVF 304
            |..:.::.|.:|        :|.       .|.|| |.|....|...||||:......||.....
  Fly   177 TVYLSQKKPFECHRNGQLLPINE-------GQFCA-GNRDRSFCRSNSGSPLTADFTYGVKNITV 233

  Fly   305 LAGIASYGQQYCYSAGIPGVYTKIGHFSEWI 335
            ..|:.|||.:.|...   .|||.:..|.:||
  Fly   234 QVGLVSYGSELCSPT---SVYTDVVAFKDWI 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	1/1 (100%)
		Tryp_SPc	108..338	CDD:238113	68/265 (26%)
		Tryp_SPc	108..335	CDD:214473	66/263 (25%)
CG33465	NP_001033950.2	Tryp_SPc	46..264	CDD:238113	65/250 (26%)
		Tryp_SPc	46..261	CDD:214473	63/248 (25%)
		Tryp_SPc	293..484	CDD:304450
		Tryp_SPc	293..481	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463665
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940