DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CG14990

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_647856.2	Gene:	CG14990 / 38486	FlyBaseID:	FBgn0035496	Length:	322	Species:	Drosophila melanogaster

Alignment Length:	279	Identity:	78/279 - (27%)
Similarity:	117/279 - (41%)	Gaps:	50/279 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 PNKQTCGQTTP--------VFRDRGAENAELNEYPWMVLLLYENRL----SLI--RYVLTAAHCV 142
            || |.||.:.|        |.:|....    .::||:|.|..:.:.    |||  ..|||||..|
  Fly    44 PN-QVCGMSNPNGLVANVKVPKDYSTP----GQFPWVVALFSQGKYFGAGSLIAPEVVLTAASIV 103

  Fly   143 IGGYLTQNDLVLKSVRLGESTT----DCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALL 203
            :|  .|..::|   ||.||..|    :.:.||.|      .|.:...|:.|:...|.  |:||||
  Fly   104 VG--KTDAEIV---VRAGEWNTGQRSEFLPSEDR------PVARVVQHREFSYLLGA--NNIALL 155

  Fly   204 RLQFPVRYTKKIQPICLLDAEFPLQDLNLQISGWDPTKSSQTLITSTVKE-----RNPADCLNRY 263
            .|..|......|:.|||.............::||.....:....::..|:     .|.|.|.::.
  Fly   156 FLANPFELKSHIRTICLPSQGRSFDQKRCLVTGWGKVAFNDENYSNIQKKIELPMINRAQCQDQL 220

  Fly   264 PSFR-------SASQVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGI 321
            .:.|       .||.:||||::....|.|..||.:...|.:....:. .|||.::|.. |....:
  Fly   221 RNTRLGVSFDLPASLICAGGEKDAGDCLGDGGSALFCPMEADPSRYE-QAGIVNWGIG-CQEENV 283

  Fly   322 PGVYTKIGHFSEWIKANLA 340
            |.|||.:..|.:||..::|
  Fly   284 PAVYTNVEMFRDWIYEHMA 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	69/251 (27%)
		Tryp_SPc	108..335	CDD:214473	67/248 (27%)
CG14990	NP_647856.2	Tryp_SPc	67..300	CDD:238113	69/251 (27%)
CG14990	NP_647856.2	Tryp_SPc	67..297	CDD:214473	67/248 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910