DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and Prss48

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001001650.1	Gene:	Prss48 / 368202	MGIID:	2685865	Length:	312	Species:	Mus musculus

Alignment Length:	281	Identity:	73/281 - (25%)
Similarity:	113/281 - (40%)	Gaps:	72/281 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 KQTCGQTTPVFRDRGAENAELNEYPWMVLLLYENRL----SLI--RYVLTAAHCVIGGYLTQNDL 152
            :..||:.....|..|.::|.|..:||.|.|.::...    |||  .:|||||||:...:.:
Mouse    28 QSVCGRPVHTGRIVGGQDAALGRWPWQVSLRFDYTHSCGGSLISDHWVLTAAHCIKKTWYS---- 88

  Fly   153 VLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTY--------------RNDIALL 203
            .|.||.||                       ::.:.::|:|..|              ..|||||
Mouse    89 FLYSVWLG-----------------------SIDREYSSTGKEYYVSRIAIPDKHRHTEADIALL 130

  Fly   204 RLQFPVRYTKKIQPICLLDAEFPLQ-DLNLQISGWDPTKSSQ----------TLITSTVKER--N 255
            :|...|.::..|.||||.:....|. ..:..::||...:...          .:|:|...|:  |
Mouse   131 KLSSRVTFSSVILPICLPNISKQLTVPASCWVTGWGQNQEGHYPSTLQELEVPVISSEACEQLYN 195

  Fly   256 PADCLNRYPSFR---SASQVCAG-GQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYC 316
            |....  .|...   .....||| .|.:.|:|.|.||.|    :...:|....|.|:.|:|.: |
Mouse   196 PIGVF--LPDLERVIKEDMFCAGERQSRKDSCKGDSGGP----LSCHIDGVWRLMGVVSWGLE-C 253

  Fly   317 YSAGIPGVYTKIGHFSEWIKA 337
             ...:|||||.:.::.:||.|
Mouse   254 -GKDLPGVYTNVTYYQKWISA 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	70/267 (26%)
		Tryp_SPc	108..335	CDD:214473	67/263 (25%)
Prss48	NP_001001650.1	Tryp_SPc	39..271	CDD:214473	68/266 (26%)
Prss48	NP_001001650.1	Tryp_SPc	40..274	CDD:238113	70/269 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910