DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and Prss3

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_001102096.1	Gene:	Prss3 / 362347	RGDID:	1311446	Length:	246	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	72/252 - (28%)
Similarity:	105/252 - (41%)	Gaps:	52/252 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 GAENAELNEYPWMVLLLYENRL---SLI--RYVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCI 167
            |....:.|..|:.|.|......   |||  ::|::||||    |.|:     ..|||||...:.:
  Rat    26 GGYTCQENSVPYQVSLNSGYHFCGGSLINDQWVVSAAHC----YKTR-----IQVRLGEHNINVL 81

  Fly   168 TSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDLNL 232
            ..:.:.    |...:...|..|.:.  ...|||.|::|..||:...::..:.|..:..|.....|
  Rat    82 EGDEQF----VNAAKIIKHPNFNAR--NLNNDIMLIKLSSPVKLNARVATVALPSSCAPAGTQCL 140

  Fly   233 QISGWDPTKSSQTLITSTVKERNP-------------ADCLNRYPSFRSASQVCAGGQRKG-DTC 283
             ||||..|.|        :...||             |||...||...:.:.:|.|....| |:|
  Rat   141 -ISGWGNTLS--------LGVNNPDLLQCLDAPVLPQADCEASYPGKITNNMICVGFLEGGKDSC 196

  Fly   284 AGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANLA 340
            .|.||.||: ..|.       |.||.|:|.. |.....||||||:.::.:||:..:|
  Rat   197 QGDSGGPVV-CNGQ-------LQGIVSWGYG-CALKDNPGVYTKVCNYVDWIQDTIA 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	71/248 (29%)
		Tryp_SPc	108..335	CDD:214473	69/245 (28%)
Prss3	NP_001102096.1	Tryp_SPc	23..239	CDD:214473	69/245 (28%)
Prss3	NP_001102096.1	Tryp_SPc	24..242	CDD:238113	71/248 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910