DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and Prss21

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_006245934.1	Gene:	Prss21 / 353251	RGDID:	727870	Length:	337	Species:	Rattus norvegicus

Alignment Length:	285	Identity:	88/285 - (30%)
Similarity:	127/285 - (44%)	Gaps:	44/285 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 PELGDVLPNKQTCGQTTPVFRDRGAENAELNEYPWM-VLLLYENRL---SLI--RYVLTAAHCVI 143
            |||.:.......||..|...|..|.|.|||..:||. .|.::.|.|   :|:  |:|||||||
  Rat    37 PELQEANLLSGPCGHRTIPSRIVGGEEAELGRWPWQGSLRVWGNHLCGATLLNRRWVLTAAHC-- 99

  Fly   144 GGYLTQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGT--YRNDIALLRLQ 206
              :...||....:|:.||     :||.....:|.....:..:...|.|...|  :.:|||||:|.
  Rat   100 --FQKDNDPFDWTVQFGE-----LTSRPSLWNLQAYSNRYQIEDIFLSPKYTEQFPHDIALLKLS 157

  Fly   207 FPVRYTKKIQPICLLDAEFPLQD-LNLQISGWDPTKSSQTL-ITSTVKE-----RNPADC--LNR 262
            .||.|:..|||||||::.:...: .:..::||......::| :.:.::|     .|...|  |.:
  Rat   158 SPVTYSNFIQPICLLNSTYKFANRTDCWVTGWGAIGEDESLPLPNNLQEVQVAIINNTMCNHLFK 222

  Fly   263 YPSFRS---ASQVCAGGQRKG-DTC---------AGISGSPVMGIMGSGVDEFVFLAGIASYGQQ 314
            .|.||.   ...||||....| |.|         .|.||.|::    ...|...:..|:.|:|..
  Rat   223 KPDFRINIWGDMVCAGSPEGGKDACFAKLTYAAPQGDSGGPLV----CNQDTVWYQVGVVSWGIG 283

  Fly   315 YCYSAGIPGVYTKIGHFSEWIKANL 339
             |.....|||||.|.|...||:..:
  Rat   284 -CGRPNRPGVYTNISHHYNWIRLTM 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	81/259 (31%)
		Tryp_SPc	108..335	CDD:214473	79/256 (31%)
Prss21	XP_006245934.1	Tryp_SPc	57..303	CDD:214473	80/259 (31%)
Prss21	XP_006245934.1	Tryp_SPc	58..304	CDD:238113	80/259 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910