DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and SPH93

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster

Alignment Length:	303	Identity:	84/303 - (27%)
Similarity:	126/303 - (41%)	Gaps:	75/303 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 CGL-DPNGHELLHMVYVCCPELGDVLPNKQTCGQTTPVFRDRGAENAELNEYPWMVLLLYENRL- 129
            ||: :.||.:::..:               |..|..|.            :|||.|.:.:..:.
  Fly   233 CGMSNANGLQMVEGI---------------TIDQARPA------------QYPWAVAIFHNGQYL 270

  Fly   130 ---SLIR--YVLTAAHCVIGGYLTQNDLVLKSVRLGE----STTDCITSESRCPHLDVEVGQTTV 185
               |||:  .|||.||.||   ..:.:||   ||.|:    |..:...||.|      ||.:..:
  Fly   271 AGGSLIQPNVVLTVAHRVI---TIETELV---VRAGDWDLKSDREIFLSEQR------EVERAVI 323

  Fly   186 HQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDLNLQISGWDPTKSSQTLITST 250
            |:||....|.  |::|||.|..|.:....|:.|||.............::||...:......::.
  Fly   324 HEGFDFKSGA--NNLALLFLNSPFKLNDHIRTICLPTPNKSFAGRRCTVAGWGKMRYEDQRYSTV 386

  Fly   251 VKE-------RNPADCLNRYPSFRSASQ-------VCAGGQRKGDTCAGISGSPVMGIMG---SG 298
            :|:       ||..:...|  |.|..::       :||||:...|||.|..||.:...:|   ||
  Fly   387 LKKVQLLVVNRNVCEKFLR--STRLGAKFELPKNIICAGGELGRDTCTGDGGSALFCSIGGENSG 449

  Fly   299 VDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIKANLAP 341
            |.|   .|||.::|.. |...|||.:||::..|:.||...|.|
  Fly   450 VYE---QAGIVNWGVG-CGQEGIPAIYTEVSKFTNWITEKLLP 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	4/17 (24%)
		Tryp_SPc	108..338	CDD:238113	75/256 (29%)
		Tryp_SPc	108..335	CDD:214473	73/253 (29%)
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	77/266 (29%)
		Tryp_SPc	252..482	CDD:214473	74/261 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910