DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and l(2)k05911

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_723797.3	Gene:	l(2)k05911 / 34731	FlyBaseID:	FBgn0284244	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	278	Identity:	82/278 - (29%)
Similarity:	123/278 - (44%)	Gaps:	61/278 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 CGQTTPVFRDR----GAENAELNEYPWMVLLLYENRL----SLI--RYVLTAAHCVIGGYLTQND 151
            ||...||..|:    |..||..:|:||:.:|....:.    |||  .::|||||||  ..:|..|
  Fly   387 CGNKNPVTPDQERIVGGINASPHEFPWIAVLFKSGKQFCGGSLITNSHILTAAHCV--ARMTSWD 449

  Fly   152 LVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQ 216
            :...:..||:..   |.::....|:...:.:...|:||..|  |..||:|:|.|..||.:|::||
  Fly   450 VAALTAHLGDYN---IGTDFEVQHVSRRIKRLVRHKGFEFS--TLHNDVAILTLSEPVPFTREIQ 509

  Fly   217 PICLLDAEFPLQDLN------LQISGWDPTKSSQTLITSTVKERNP---------------ADCL 260
            ||||..:  |.|...      ..::||           .:::|..|               |:|.
  Fly   510 PICLPTS--PSQQSRSYSGQVATVAGW-----------GSLRENGPQPSILQKVDIPIWTNAECA 561

  Fly   261 NRY----PSFRSASQVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGI 321
            .:|    |.....|.:|| ||...|:|:|.||.|::...|....:    .||.|:|.. |.....
  Fly   562 RKYGRAAPGGIIESMICA-GQAAKDSCSGDSGGPMVINDGGRYTQ----VGIVSWGIG-CGKGQY 620

  Fly   322 PGVYTKIGHFSEWIKANL 339
            |||||::.....||..|:
  Fly   621 PGVYTRVTSLLPWIYKNI 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	76/260 (29%)
		Tryp_SPc	108..335	CDD:214473	74/257 (29%)
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		Tryp_SPc	399..634	CDD:214473	74/260 (28%)
		Tryp_SPc	400..637	CDD:238113	76/262 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910