DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and ela2l

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_956180.1	Gene:	ela2l / 334304	ZFINID:	ZDB-GENE-040511-1	Length:	267	Species:	Danio rerio

Alignment Length:	266	Identity:	78/266 - (29%)
Similarity:	118/266 - (44%)	Gaps:	37/266 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 TCGQTT--P-VFRDRGAENAELNEYPWMVLLLYENRL--------SLI--RYVLTAAHCVIGGYL 147
            :||..|  | |.|..|..:...|.:||.:.|.|::..        |||  ::|||||||:.....
Zfish    16 SCGLPTFPPIVTRVVGGVDVRPNSWPWQISLQYKSGSNWYHTCGGSLIDKQWVLTAAHCISSSRT 80

  Fly   148 TQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYT 212
            .:       |.||:.:    .|:.....:.:..|:..||:.:.|.  |.||||||::|:..|...
Zfish    81 YR-------VFLGKHS----LSQEENGSVAIGAGKIIVHEAWNSF--TIRNDIALIKLETAVTIG 132

  Fly   213 KKIQPICLLDAEFPL-QDLNLQISGWDPTKSSQTLITSTVKERNP----ADCLNR--YPSFRSAS 270
            ..|.|.||.:|.:.| .:....::||....::..|.....:...|    |.|...  :.|..:.|
Zfish   133 DTITPACLPEAGYVLPHNAPCYVTGWGRLYTNGPLADILQQALLPVVDHATCSKSDWWGSQVTTS 197

  Fly   271 QVCAGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQY-CYSAGIPGVYTKIGHFSEW 334
            .|||||......|.|.||.|:......|..|   :.||.|:|... |.....|.|:|::..:|:|
Zfish   198 MVCAGGDGVVAGCDGDSGGPLNCAGSDGAWE---VHGIVSFGSGLSCNYNKKPTVFTRVSAYSDW 259

  Fly   335 IKANLA 340
            |..|:|
Zfish   260 ISKNMA 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	70/247 (28%)
		Tryp_SPc	108..335	CDD:214473	68/244 (28%)
ela2l	NP_956180.1	Tryp_SPc	28..260	CDD:214473	69/247 (28%)
ela2l	NP_956180.1	Tryp_SPc	29..263	CDD:238113	70/249 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910