DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and CG11911

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_608518.1	Gene:	CG11911 / 33206	FlyBaseID:	FBgn0031249	Length:	277	Species:	Drosophila melanogaster

Alignment Length:	248	Identity:	70/248 - (28%)
Similarity:	114/248 - (45%)	Gaps:	41/248 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 GAENAELNEYPWMVLL----LYENRL---SLIR--YVLTAAHCVIGGYLTQNDLVLKSVRLGEST 163
            |.| ||.:..|::|.|    |..:.:   :||.  :::|||||:       ::.|..|:..|..|
  Fly    40 GTE-AEPHSAPYIVSLATNYLKHSHICGGTLINKDWIVTAAHCI-------SEPVGMSIIAGLHT 96

  Fly   164 ---TDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQFPVRYTKKIQPICLLDAEF 225
               .|.:|.:.:     |:.|:  ||:.:|...|.|  |||||.:.....:.:.:||..|...|
  Fly    97 RAEVDELTQQRQ-----VDFGR--VHEKYTGGVGPY--DIALLHVNESFIFNEWVQPATLPSRE- 151

  Fly   226 PLQDLNLQISGWDPTKS-----SQTLITSTVKERNPADCLNRYPSFR--SASQVCAGG-QRKGDT 282
            .:.:....:.||...||     ::||.|.|.:..|..:|....|...  :.|.:|:.. |:....
  Fly   152 QVHEGETHLYGWGQPKSYIFSGAKTLQTVTTQILNYEECKEELPESAPIAESNICSSSLQQSKSA 216

  Fly   283 CAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWI 335
            |.|.||.|::....:...|   |.||.|:|...|..|.:|.:|||:..:.:||
  Fly   217 CNGDSGGPLVVEFTNAPSE---LIGIVSWGYIPCGLANMPSIYTKVSAYIDWI 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	70/248 (28%)
		Tryp_SPc	108..335	CDD:214473	68/246 (28%)
CG11911	NP_608518.1	Tryp_SPc	37..269	CDD:238113	70/248 (28%)
CG11911	NP_608518.1	Tryp_SPc	37..266	CDD:214473	68/246 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910