DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and AgaP_AGAP005687

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	XP_556332.3	Gene:	AgaP_AGAP005687 / 3290023	VectorBaseID:	AGAP005687	Length:	297	Species:	Anopheles gambiae

Alignment Length:	287	Identity:	75/287 - (26%)
Similarity:	117/287 - (40%)	Gaps:	72/287 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 PNKQTCGQTTPVFRDRGAENAELNEYPWMVLLL--YENRLSLI-------RYVLTAAHCVIGGYL 147
            |..|.....|...|....:.|...::|:.|.||  :.:..:|.       .::|||||||..
Mosquito    43 PELQVYRNDTSTDRVVNGQEALPGQFPYQVALLLNFPDGTALCGGSVLTRNFILTAAHCVSA--- 104

  Fly   148 TQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSG---------GTYRNDIALL 203
            |...||...:.:       :.:.:|..   :|:.|..:.  |||:|         .:.|||:||:
Mosquito   105 TSTTLVSGGIAI-------MGAHNRTA---MELSQQRIR--FTSTGIRRHPEYDDTSLRNDVALI 157

  Fly   204 RLQFPVRYTKKIQPICLLDAEFPLQDLNLQISGW-------------DPTKSSQTLITSTVKERN 255
            .|..|:.:|.:::||.|     |.:....|..|:             .|..||....||     |
Mosquito   158 LLNSPMTFTSRVKPISL-----PARTDTRQFEGFTGTVSGFGRSSDASPYPSSILRFTS-----N 212

  Fly   256 P----ADCLNRYPSFRSASQ-VC---AGGQRKGDTCAGISGSPVMGIMGSGVDEFVFLAGIASYG 312
            |    |:|:..:....:.|| ||   .||:   .:|.|.||.|:....|.     |...|..|:|
Mosquito   213 PIMSKAECIVSWGFALAQSQNVCLKPTGGR---SSCNGDSGGPLTVNSGG-----VLQIGTVSFG 269

  Fly   313 QQYCYSAGIPGVYTKIGHFSEWIKANL 339
            ..|..::|.|.||.::.:|..||..|:
Mosquito   270 SSYGCASGWPSVYARVSYFLSWINENI 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	70/268 (26%)
		Tryp_SPc	108..335	CDD:214473	68/265 (26%)
AgaP_AGAP005687	XP_556332.3	Tryp_SPc	56..292	CDD:214473	69/268 (26%)
AgaP_AGAP005687	XP_556332.3	Tryp_SPc	57..295	CDD:238113	70/270 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910