DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and plg

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_958880.2	Gene:	plg / 322691	ZFINID:	ZDB-GENE-030131-1411	Length:	818	Species:	Danio rerio

Alignment Length:	348	Identity:	91/348 - (26%)
Similarity:	146/348 - (41%)	Gaps:	102/348 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 GMT-QAEKDVFAHRQCGLDPNGHELLHMVYVCCPELG-----------DVL--------PNKQ-- 95
            |:| ||.:.:..|:.....|..|          |:.|           ||.        |:|:
Zfish   509 GVTCQAWRSMTPHQHASFTPETH----------PDKGLESNQCRNPDSDVNGPWCYTTDPSKKWD 563

  Fly    96 ----------TCGQ--TTP---VFRDRGAENAELNEYPWMVLLLYENRL-----SLI--RYVLTA 138
                      .|||  |.|   ..|..|...::.:.:||.:.|....::     :||  ::|:||
Zfish   564 YCQIPDCESLKCGQPATKPKRCFGRIVGGCVSKPHSWPWQISLRTRGKIHFCGGTLIDPQWVVTA 628

  Fly   139 AHCVIGGYLTQNDL-VLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIAL 202
            |||     |.::|. ....:.||..|..  .:||.....||    |.:.:|   ..||   ||||
Zfish   629 AHC-----LERSDSPSAYKIMLGIHTER--ATESSKQERDV----TKIIKG---PAGT---DIAL 676

  Fly   203 LRLQFPVRYTKKIQPICLLDAEFPL-QDLNLQISGWDPTKSS-------QT---LITSTVKERNP 256
            |:|..|.....|:.|:||.:.::.: .:....::||..|:.:       :|   :|.:.|..|
Zfish   677 LKLDRPALINDKVSPVCLPEKDYIVPSNTECYVTGWGETQDTGGEGYLKETGFPVIENKVCNR-- 739

  Fly   257 ADCLNRYPSFRSA----SQVCAGGQRKG-DTCAGISGSPVMGIMGSGVDEFVFLAGIASYGQQYC 316
                   |||.:.    .::|||....| |:|.|.||.|   ::....:.|| |.|:.|:|.. |
Zfish   740 -------PSFLNGRVKDHEMCAGNIEGGNDSCQGDSGGP---LVCYAQNTFV-LQGVTSWGLG-C 792

  Fly   317 YSAGIPGVYTKIGHFSEWIKANL 339
            .:|..|||||::..|.:||:.::
Zfish   793 ANAMKPGVYTRVSKFVDWIERSI 815

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	7/31 (23%)
		Tryp_SPc	108..338	CDD:238113	72/253 (28%)
		Tryp_SPc	108..335	CDD:214473	70/250 (28%)
plg	NP_958880.2	PAN_AP_HGF	31..104	CDD:238532
		KR	109..190	CDD:214527
		KR	190..270	CDD:214527
		KR	281..361	CDD:214527
		Kringle	376..453	CDD:306546
		KR	490..572	CDD:214527	13/72 (18%)
		Tryp_SPc	589..813	CDD:238113	72/254 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910