DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18754 and sphinx1

DIOPT Version :9

Sequence 1:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster
Sequence 2:	NP_729255.2	Gene:	sphinx1 / 318005	FlyBaseID:	FBgn0052383	Length:	253	Species:	Drosophila melanogaster

Alignment Length:	243	Identity:	46/243 - (18%)
Similarity:	83/243 - (34%)	Gaps:	70/243 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 VIGGYLTQNDLVL------------KSVRLGESTTDCITSES---------RCPHLDVEVGQTTV 185
            :.|||..:...::            .|:..|..|   |.|..         :..:::|.:.....
  Fly    26 IAGGYRAKTFTIIYLVGIVYFKSQTSSLNYGAGT---IISNQWILTVKTVLKYSYIEVHLASRRS 87

  Fly   186 HQGF-------TSSGGTYRND--IALL------------RLQFPV------RYTKKIQPICLLDA 223
            ::||       .:....|.||  |||:            |::.|.      ||...:..:|
  Fly    88 YRGFDIIRIYKENFRFHYDNDHVIALVKCPYQKFDRRMDRVRVPAYDTRFERYVGNMTMVC---- 148

  Fly   224 EFPLQDLNLQISGWDPTKSSQTLITSTVKERNPADCLNRYPSFRSASQVCAGGQRKGDTCAGISG 288
            .:..:..:.::..|        :....|:..|..:|...|...: ..::|..|:.....|.|..|
  Fly   149 GYGTEKRHAKLPEW--------MRCIEVEVMNNTECAKYYTPLK-WYEMCTSGEGFKGVCEGDIG 204

  Fly   289 SPVMGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWIK 336
            ..|: .||.. ..|:   ||.....:.| |.|.|.|:.::....:|||
  Fly   205 GAVV-TMGPN-PTFI---GIIWLMPENC-SIGYPSVHIRVSDHIKWIK 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	46/243 (19%)
		Tryp_SPc	108..335	CDD:214473	43/240 (18%)
sphinx1	NP_729255.2	Tryp_SPc	25..245	CDD:214473	43/240 (18%)
sphinx1	NP_729255.2	Tryp_SPc	26..248	CDD:304450	46/243 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436383
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030